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You have a degree in a biological science and are capable of quickly coming up to speed on the biologics drug discovery process. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma.
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Experience in high-impact contributions to biomarker discovery and/or assay development. Lead and/or contribute to clinical asset biomarker strategy within early and late-stage clinical development antibody drug conjugate (ADC) programs to generate data that informs on target engagement, pharmacodynamics, mechanism of action and patient selection.
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You will have experience in inflammatory disease, fibrotic and extra-cellular matrix pathobiology, innate and adaptive cell biology and associated in vivo models of disease to join the Gastro-Intestinal Inflammation Research (Drug Discovery Unit.
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Oversees (NS, GI2 or ONC) project portfolio as the DMPK Leadership Team nominee, ensuring that the DMPK strategy is in alignment with other functions in discovery and development. Provides scientific and strategic expertise to DMPK Project Team Representatives for the development of TA drug candidates.
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Integrate drug metabolism and pharmacokinetics (DMPK) predictions into bioanalytical workflows to support early-phase drug development and optimization. Extensive experience with pharmacokinetic and biodistribution studies of antibody-drug conjugates and relevant analytical methods including LC-MS/MS for small molecule quantitation and MSD for ELISA and LBbased assays.
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Collaborate within the Discovery team on biochemistry and biophysics projects and provide cell biology expertise and guidance to junior team members. Lead cell biology efforts within the Discovery team to identify and implement relevant cell-based assays for diverse target classes and disease areas (immunology, oncology, metabolism.
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Embody Dana-Farber’s Core Values: Impact; Excellence; Compassion & Respect; Discovery; and Equity and Inclusion every day. Philanthropy raised through The Dana-Farber Campaign is focused on accelerating the Institute’s strategic priorities by supporting revolutionary science, extraordinary care, exceptional expertise, and essential opportunities—helping us prevent, treat, and Defy Cancer.
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Primarily act as a key expert for DMPK and safety assessment during the drug discovery phase, providing specific knowledge and expertise to cross-functional project teams (including clinical, CMC and regulatory functions) and communicating with clarity the predicted implications of new targets/therapeutic concepts.
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The Chemical Biology and Proteomics (CBP) group at Biogen is seeking a creative and self-motivated Research Fellow to design, develop, and apply existing and new target identification strategies to various drug discovery programs.
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Working both independently and collaboratively to support cutting-edge Oncology drug discovery biology programs. The ideal candidate will thrive in a collaborative environment and make meaningful contributions as a valued member of our dynamic drug discovery team.
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Collaboration with his/her clinical team, the VP Discovery, VP Precision & Translational Medicine, VP Preclinical, Head of Regulatory, CSO, CTO and CMO is critical to ensure alignment on portfolio priorities and ensure that resources are managed appropriately to advance programs to key inflection points.
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The Principal Scientist of Analytical Development and QC at Foghorn Therapeutics will drive the analytical development and QC functions, ensuring the successful advancement of small molecule candidates from preclinical through NDA for both drug substances and drug products.
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Our approach begins by targeting the root causes of disease, using deep scientific knowledge in our core focus areas and drug discovery expertise across multiple therapeutic modalities. Ensure the precise and timely initiation of expense reports, directly connecting expenses to budgetary guidelines and implement a rigorous tracking system to monitor expenditures, ensuring budget adherence, and financial accuracy in partnership with Financial Planning & Analysis partner.
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Previous experience working on drug discovery projects. Innova Solutions is immediately hiring for a Scientist - III Job Title: Scientist - III Location: Cambridge, Massachusetts Duration: 24 Months Responsibilities: The candidate will perform functional assays with iPS-derived human microglia and help develop brain organoid model systems to identify and validate neuroimmune drug targets.
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The ElevateBio ecosystem combines multiple R&D technology platforms – including Life Edit, a next-generation, full-spectrum gene editing platform; comprehensive cell engineering technologies; and an expanded viral and non-viral therapeutic delivery platform – with BaseCamp®, its end-to-end genetic medicine cGMP manufacturing and process development business, to accelerate the discovery and development of advanced therapeutics.
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drug discovery jobs Title: doctoral in Cambridge, MA
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