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Lead internal process development, optimization and tech transfer of upstream and downstream process development for clinical development pipeline. Extensive experience selecting and overseeing CDMO’s for tech transfer of protein manufacturing including both upstream and downstream methods.
Full-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Prepare buffers for downstream (homogenization, solubilization, and protein purification) operations. The Research Associate I, Downstream CMC (Contract) position will support the Company’s intracellular biologics discovery programs.
ExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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Lead and oversee the development, optimization and tech transfer of bispecific protein therapeutics. Tech transfer of methods and processes to CDMO for early stage clinical manufacturing. Seasoned leader with extensive industry experince in biologic CMC and process development at the VP level.
Full-timeExpandApply NowActive JobUpdated 12 days ago - UpvoteDownvoteShare Job
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Production experience with proteins expressed and refolded from E. coli and with proteins expressed in mammalian cells with oversight of both upstream and downstream process development. Develop and optimize upstream and downstream processes to generate lead and Development Candidate TCR bispecific and to enable seamless technology transfer to contract manufacturing organizations.
$185,000 a yearFull-timeExpandApply NowActive JobUpdated 4 days ago - UpvoteDownvoteShare Job
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Knowledge of how to implement QC requirements with a variety of downstream in-vitro and in-vivo uses. Understanding the importance of how to develop production workflows and appropriate QC for in-vivo grade products is essential to the role as downstream uses include immunogenicity assays, in-vivo PK, efficacy, and toxicology studies.
Full-timeExpandApply NowActive JobUpdated 16 days ago - UpvoteDownvoteShare Job
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Providing analytical support to Upstream and Downstream process development team activities by ensuring consistent and timely execution of standardized platform product characterization assays, including data review, storage and trending.
Full-timeExpandApply NowActive JobUpdated 15 days ago - UpvoteDownvoteShare Job
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Significant hands-on experience in upstream/downstream process development studies with biologics. Assist in leading cell line, upstream and downstream process development activities from lab scale to GMP scale at Drug Substance CDMOs.
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CQV Engineer - Downstream - Life Sciences - Contract - Massachusetts Our client, a leading partner to pharmaceutical, biotech and nutrition markets, has an exciting opening for a CQV Engineer – Downstream for their new Capex investment project.
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The candidate contributes to the Viral Vector Process Development group through the design and execution of experiments based around downstream AAV (Adeno-Associated Virus) manufacturing processes.
$122,000 a yearFull-timeExpandApply NowActive JobUpdated 13 days ago - UpvoteDownvoteShare Job
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15 plus years' experience in pharma/biotech industry with significant management experience in upstream/downstream process development and manufacturing of protein therapeutics. We are seeking a senior CMC leader with experience to advance our TCR bispecific therapies from lead candidate to clinical development, including internal upstream and downstream development of robust manufacturing processes as well as tech transfer and oversight of cGMP manufacturing at external contract development and manufacturing organizations (CDMOs.
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Experience in downstream process development is ideal. We are seeking a Research Associate or Senior Research Associate to join a team focused on process development of messenger RNA (mRNA) for Verve’s novel CRISPR gene editing therapies.
Full-timeExpandApply NowActive JobUpdated 10 days ago - UpvoteDownvoteShare Job
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15+ years of experience in biologics drug development or manufacturing in biotech or biopharma industry, with significant hands-on experience in areas of downstream process development and tech transfer, BLA enabling study and PPQ, commercial manufacturing, commercial supply, and product life cycle management.
$255,000 a yearFull-timeExpandApply NowActive JobUpdated 10 days ago - UpvoteDownvoteShare Job
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We're looking for someone exceptional to join our growing team as a Sr. Scientist, Downstream in the Process Development group. Work closely with Research, Upstream Process Development, Formulation Development, and Analytical groups to achieve top-tier product purity and potency.
Full-timeExpandApply NowActive JobUpdated 15 days ago - UpvoteDownvoteShare Job
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The ideal candidate will have a diverse set of skills including 5+ years of experience with product / crude / fuels scheduling and logistics, refinery operations, refinery planning / economics, downstream strategy, logistics, hedging and trading operations (crude, feedstocks, products, intermediates.
$265,100 a yearFull-timeExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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Train and transfer testing and optimization of downstream oligonucleotide processing including chromatographic purification methods to new or existing team member. Accordingly, plan and execute process development studies (upstream/downstream) with the objective to introduce process improvements into the GMP manufacturing of sgRNA. Support associated tech transfers.
Full-timeExpandApply NowActive JobUpdated 16 days ago
downstream job in Cambridge, MA
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