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Preferred Qualifications: Experience in handling, formulating, processing, and characterizing gene therapy drug product, such as adeno-associated virus (AAV) and lipid nanoparticles (LNPs). Knowledge of gene therapy drug product process development, fill-finish, lyophilization, and process modeling.
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Prologue Medicines is dedicated to transforming drug discovery by leveraging deep biological insights and cutting-edge scientific innovations. Develop and validate immunological assays (, flow cytometry, ELISA, CyTOF, cytokine profiling) to evaluate drug candidates' efficacy and mechanism of action.
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For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development.
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Many of our programs are derived from our TRACER AAV capsid discovery platform, which we have used to generate novel capsids and identify associated receptors to potentially enable high brain penetration with genetic medicines following intravenous dosing.
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LanceSoft specializes in providing Registered Nurses, Nurse Practitioners, LPNs/LVNs, Social Workers, Medical Assistants, and Certified Nursing Assistants to work in Acute Care Centers, Skilled Nursing Facilities, Long-Term Care centers, Rehab Facilities, Behavioral Health Centers, Drug & Alcohol Facilities, Home Health & Community Health, Urgent Care Clinics, and many other provider-based facilities.
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We are seeking a highly motivated Principal Associate Scientist with experience in cellular and molecular biology techniques for drug discovery. FogPharma is a biopharmaceutical company pioneering the discovery and development of Helicon™ therapeutics, which are peptides capable of efficient cell entry and modulation of both protein-protein and protein-DNA interactions.
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Collaboration with his/her clinical team, the VP Discovery, VP Precision & Translational Medicine, VP Preclinical, Head of Regulatory, CSO, CTO and CMO is critical to ensure alignment on portfolio priorities and ensure that resources are managed appropriately to advance programs to key inflection points.
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Experience in providing scientific and technical leadership applied to novel assay development, advancing challenging drug discovery programs, and mentoring junior colleagues. To this end, this role will collaborate closely with research and program teams to support the identification and characterization of new targets and the discovery of therapeutics in new indications areas, including neurological diseases.
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Extensive experience in CMC pharmaceutical development for active pharmaceutical ingredients and drug products under cGMP’s. This role sits in Biotherapeutics Process Development (BPD) and is responsible for guiding and leading all late-stage development activities for Biologics Drug Substance Process Development.
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Performs histochemical, IHC, and IF staining using automated platforms such as Leica Autostainer XL, Ventana Discovery ULTRA, Leica BOND RX and Vectra Phenoimager XT Perform image capture and analysis, data entry and organization using platforms such as (but not limited to) Leica Aperio imager and associated software.
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This position offers an exciting opportunity to impact human health through innovative human genomics research, and will enable discovery groups within BMS research to launch novel programs based on causal human biology.
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Ph. D. with minimum of 15 years of working experience, including proven track record in the discovery and development of drugs for diseases of peripheral tissues/organs in the pharmaceutical and/or biotechnology industry, substantiated by publications, patent filings, and/or other, from tenure in drug discovery and development as characterized.
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Provide process and technical leadership in the manufacturing process operations for Drug Substance, including but not limited to: Solution preparation, Adherent and suspension cell culture, Operation of Wave and disposable, single use Bio reactors, Chromatography and Tangential Flow Filtration & Viral Filtration.
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Experience in and understanding of end-to-end management of clinical trial conduct, the pharmaceutical industry, clinical drug development, clinical trials operations and regulatory components is essential.
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Who We Are: MapLight Therapeutics is a clinical stage biotech company that focuses on drug discovery for central nervous system disorders. We combine cutting-edge technologies including optogenetics, in vivo physiology, and spatial transcriptomics to identify novel drug targets and develop effective therapies to address psychiatric symptoms.
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drug discovery jobs Title: doctoral in Burlington, MA
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