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Ampersand is currently seeking a highly motivated, passionate, and detail-oriented Research Associate I/II to join our Protein Sciences team. The ideal candidate will have hands-on experience working with mammalian cell culture, protein expression, purification and analytical QC using diverse biochemical methods such as ELISA, SDS-PAGE, Western blotting.
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The Center for Protein Degradation (CPD) is seeking a biologist/biochemist to join the Biochemistry and Structural Biology team. Dana-Farber Cancer Institute (DFCI) and Deerfield Management have created the Center for Protein Degradation (CPD) at DFCI. The CPD has created a next-generation protein degrader and molecular glue platform to advance novel therapeutic modalities.
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We can accomplish our mission by building deep expertise in large molecule end-to-end discovery such as Antibody discovery, protein engineering and optimization, molecular attribute characterization, target protein & expression sciences, and platform biology/in vitro pharmacology/assay development.
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Additional skills to support downstream characterization as needed would be beneficial and could include: protein expression and purification using FPLC systems and biophysical characterization methods (SEC-MALS, DSF, and biosensor techniques including BLI and SPR.
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Your cross-disciplinary colleagues from Computational Chemistry, Medicinal Chemistry, Computational Biology, Cell Biology, and Pharmacology, how the protein design platform can be applied in their structure-based design of small molecule therapeutics.
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Characterize recombinant proteins using SDS-PAGE, WB, protein quantitation, HPLC, ELISA and other biochemical/biophysical assays such as BLI and SPR to determine protein purity and function.
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You'll be up-to-date on latest published developments in synthetic biology, generative AI, protein, and cell biology. Developing and executing high-throughput functional assays, cell culture, and molecular biology workflows to characterize and validate novel protein designs.
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The candidate will supervise, motivate, and grow the immunology and protein engineering groups. Orbital is seeking a Vice President of Translational Biology with expertise in immunology including vaccine, autoimmunity, and protein therapeutics.
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Knowledge and skills in chemistry and biochemistry (e.g. medicinal chemistry, bioanalytical chemistry, protein chemistry, protein expression) PhD in a scientific discipline with a minimum of 2 years industry experience (may include post doctoral experience), or a MS with a minimum of 4 years industry experience, or a BS with a minimum of 6 years industry experience.
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Seismic Therapeutic, a biotechnology startup focused on the intersection of structure, protein engineering, machine learning and immunology, is seeking an experienced and motivated Associate Scientist to help drive novel immunotherapy programs.
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The mission of Biogen’s Biologics Drug Discovery group is to design, optimize, and develop high-quality differentiated protein therapeutics that become transformative medicines. Using new technologies, cutting-edge science, and strong internal and external partnerships, we are leveraging our expertise in antibody discovery, protein and cell engineering, and biochemistry to transform the field of neuroscience.
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Familiarity with high-plex protein staining platforms and precision profiling techniques (Visium , GeoMx, CosMx) not required, but preferred. This role involves performing immunohistochemical assays, with a focus on multiplex IHC, to analyze protein expression in FFPE patient tumor biopsies generated during BioNTech clinical trials.
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We combine this and other high-throughput protein engineering approaches with computational design to create antibody-like drugs and other biologics. This is a unique opportunity to work with world-class technologists innovating in cutting edge molecular biology and compute approaches to realize the potential of a novel protein engineering platform.
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Expertise and hands on experience in liquid chromatography, protein chemistry and mass spectrometry of protein molecules, including glycoproteins, experience in LC and LC-MS method development and qualification.
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This includes understanding concepts such as protein structure and function, enzyme kinetics, molecular biology techniques, and cellular signaling pathways. Scientific Knowledge: A strong foundation in discovery sciences and protein biochemistry is essential.
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protein job Title: post doctoral associate Company: University Of Minnesota in Boston, MA
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