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Additional skills to support downstream characterization as needed would be beneficial and could include: protein expression and purification using FPLC systems and biophysical characterization methods (SEC-MALS, DSF, and biosensor techniques including BLI and SPR.
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Bachelor's or Master's degree in Biochemistry, Chemistry, or a related field with a minimum of 3 years of protein purification experience. Experience with FPLC systems and with affinity, IEX and SEC protein purification methods is desirable.
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Principal Scientist, Protein Production and Process Development. and with proteins expressed in mammalian cells with oversight of both upstream and downstream process development. Academic/PhD degree in Biochemistry, Biology, Bioengineering, Immunology, or related discipline.
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Strong grasp of biochemical methods for protein purification, including affinity, IEX, SEC, HIC, and MMC. Sr. Scientist/Principal Scientist– Protein Biochemist. · Ph. D. in Biochemistry, Biophysics, Structural Biology, or related field or B.Sc./M.Sc. with 2+ years of relevant experience in the Biotech Industry.
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The work will involve protein expression, protein purification, molecular cloning, cell culture work, and structure determination. REQUIRED: bachelor's degree in biochemistry, genetics, biophysics, molecular biology or related field; at least two years of work experience in a biochemistry/molecular biology laboratory (this may include experience gained as an undergraduate); strong interpersonal skills; and the ability to work both independently and as part of a team.
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The purification group is responsible for non-GMP protein-drug lead generation, supporting the various Pharmaceutical research units and their pre-clinical therapeutic in-vitro and in-vivo needs.
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Performs specific lab procedures including DNA cloning, cell culture, subunit protein production & purification, adenovirus vector-vaccine production and purification, mRNA/self-amplifying RNA/circRNA production and mRNLNP vaccine fabrication, PCR, qPCR, ELISA, western blot and other assays as needed.
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Protein purification by chromatography-based methods (affinity, ion exchange, size-exclusion, use of FPLC systems for semi-automated purifications is preferred) Previous experience with recombinant protein expression and purification preferred.
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Skills: HPLC, SOP, In Vitro, In Vivo, Protein Purification, GMP (Good Manufacturing Practice) The purification group is responsible for non-GMP protein- drug lead generation, supporting the various company research units and their pre-clinical therapeutic in- vitro and in- vivo needs.
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Cell culture, immunohistochemistry, molecular assays, Western blotting, protein purification, ELISA, etc) and synthesizes and interprets results. Required Qualifications:Bachelor's degree required in Biology, Biochemistry, Genetics, Engineering, Physiology, Life Science or a related scientific field.
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The Center for Protein Degradation (CPD) is seeking a biologist/biochemist to join the Biochemistry and Structural Biology team. Dana-Farber Cancer Institute (DFCI) and Deerfield Management have created the Center for Protein Degradation (CPD) at DFCI. The CPD has created a next-generation protein degrader and molecular glue platform to advance novel therapeutic modalities.
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Experience with molecular biology techniques such as DNA and RNA extraction, qPCR, protein quantification, ELISA, and enzymatic assays is required. BA/BS or MS in molecular biology, biochemistry, metabolism, or related field with 2-5 years of experience in drug discovery research.
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The purification group is responsible for non-GMP protein- drug lead generation, supporting the various research units and their pre-clinical therapeutic in- vitro and in- vivo needs. General knowledge on protein purification, protein conjugation, HPLC analysis, SDS-PAGE analysis and mass spectrometric analysis of protein.
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Seeking a highly motivated scientist to support the molecular biology & protein production workflows: DNA construct design/assembly, sample preparation for sequencing, DNA production & quantitation, mammalian cell culture & transfections, protein purification & quantitation, and automated liquid handling.
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Strong understanding of protein biochemistry or biophysics related to protein structure/function. Ph D with 5+ years of research experience in Bioinformatics, Computational Biology, Biochemistry, Biophysics, or a related biological science field.
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downstream biochemistry protein purification jobs in Boston, MA
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