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Your work will be instrumental in building and optimizing a molecular instruction set that enables the world’s first DNA storage and computing platform. CATALOG, a Boston-based pioneering startup, is a leader in the field of data storage and computation by harnessing the power of DNA. DNA, known for its millennia-long stability, unrivaled information density, and cost-effective replicability, offers revolutionary potential for latency-tolerant high-density data storage and massively parallel computation.
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The BEP production groups are looking for a laboratory technician to provide DNA, RNA and protein production support for the RNA and protein activities in BEP. The candidate is expected to have a background in biochemistry techniques including nucleic acids, protein purification, and cell culture.
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Bachelor’s degree and one (1) year of previous HLA experience or molecular genetics laboratory experience, preferably including DNA extractions, PCR amplification, probe hybridization/detection or DNA sequencing.
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Scientific training and hands-on experience with various cell-based and molecular assays, including but not limited to 2D and /3D cell culture, cell-based potency assay, ELISA, western, qPCR, RT-qPCR, and DNA/RNA/protein extraction from cells and animal (including NHP) tissues.
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Laboratory experience and knowledge of laboratory processes (PCR, Serial Dilution, Normalization, DNA Extraction, NGS, etc. Their products are used in Genomics, NGS Sample Prep, Cell Biology, Proteomics, Drug Discovery, Analytical Chemistry, Molecular Diagnostics, Biobanking, and other applications.
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Common molecular and biochemical techniques (DNA/RNA isolation, qPCR, Western, ELISA, antibody characterization and QC, etc.) Common molecular and biochemical techniques (DNA/RNA isolation, qPCR, Western, ELISA, antibody characterization and QC, etc.
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Perform molecular techniques including DNA/RNA isolation, PCR, qRT-PCR, gene expression analysis, cell line engineering and tissue culture as needed. Hands-on experience in tissue culture, plate-based assays, RNA isolation, gene expression analysis (qPCR), western blot, ELISA, multiplex protein analysis, flow cytometry preferred.
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Possess professional knowledge of Federal, State and local regulations pertaining to Center of Disease Control Prevention (CDC) and National Institutes of Health (NIH) guidelines for biosafety as they apply to infectious agents, recombinant DNA and bloodborne pathogens.
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Must have hands-on experience analyzing DNA/RNA by a variety of techniques (e.g. IP-RP, IEX, LC-fluor, multi-modal LC, etc. PhD in Chemistry, Biophysics, Biochemistry, Bioengineering, or related life sciences field with strong scientific background.
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Under the general supervision of the investigator, performs complex laboratory experiments in the field of cell biology including: cell culture, ELISA, DNA/RNA isolation, PCR, general biochemistry, immunohistochemistry, flow cytometry, and microscopy.
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Screen offspring of several mouse strains by preparation of genomic DNA and PCR or by isolation of blood cells and flow cytometry. A Research Assistant is wanted to assist with ongoing experiments that include human beta cell culture, molecular biology techniques, flow cytometry, histology, mammalian cell culture and animal studies, and banking of human and mouse iPS cells.
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DNA characterization and quality control testing using techniques such as gel electrophoresis, RNaseA testing, nanodrop, PCR, and preparation of samples for sequencing analysis (Sanger and NGS.
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Strong laboratory skills and a high degree of attention to detail with the experience in following molecular biology and analytical techniques: PCR, gel electrophoresis, gel imaging, SDS-PAGE Mammalian cell culture, transfection, transduction (AAV) Nucleic acid preparation (DNA, RNA), ddPCR, qPCR and data analysis.
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Candidates should be familiar with standard wet lab techniques (e.g. preparation of reagents/chemicals, tissue culture, PCR, western blot, DNA/RNA purification) and motivated to learn new protocols.
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Perform serologic, molecular and immunologic procedures that may include, but are not limited to, DNA extraction, PCR amplification, sequence-based typing, STR analysis, probe hybridization/detection, cytotoxic crossmatching, antibody screening/identification by Luminex and/or ELISA assays and other procedures as defined.
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dna job in Boston, MA
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