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As a member of the small molecule drug discovery division, the successful candidate will leverage their advanced protein biochemistry skills to contribute to small molecule drug discovery programs and work collaboratively with cross-functional teams to further advance these innovative projects.
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The GRC Genomic Technologies Group GTECH supports preclinical and clinical research teams by applying genomic profiling technologies with the goal of improving the success rates for drug discovery and development.
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They must be adept at applying these methods to large datasets for predictive modeling; in this context- drug properties and discovery patterns in ADME datasets. Apply computational tools and machine learning/deep learning techniques to analyze and interpret complex biological data relevant to drug discovery.
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Demonstrated record of high-proficiency, hands-on molecular biology experience with PCR-based assays and technical knowledge of high-throughput genomic profiling technologies with emphasis on Illumina sequencing platforms and complex library preparation workflows for bulkRNseq, 10X Genomics scRNseq, and 10X Genomics Visium spatial transcriptomics.
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We supports preclinical and clinical research teams by applying genomic profiling technologies with the goal of improving the success rates for drug discovery and development. Molecular biology/NGS technical knowledge.
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Typically, 7 years of experience, master's degree, or equivalent education and typically 5 years of experience in molecular biology, genetics, genomics or a related field. The core mission of the group is to apply genomics and genetics research to target discovery, target validation, translational research, and design and analysis of clinical trials.
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Maintaining familiarity with laws that affect the business and provide basic counseling on those laws, including those relevant to sales and marketing of products to healthcare professionals and reimbursement by government programs including, for example, laws related to fraud and abuse (Anti-Kickback Statute, False Claims Act), FDA regulation (Food, Drug & Cosmetic Act), privacy (HIPAA), and anti-corruption (Foreign Corrupt Practices Act.
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AbbVie Biotherapeutics and Genetic Medicine is an integrated, global discovery organization responsible for biotherapeutics drug research across disease areas including immunology, oncology, virology, neuroscience, and eye care.
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Abbott Molecular is a leader in molecular diagnostics and the analysis of DNA, RNA, and proteins at the molecular level. Executes and provides strategic updates / course corrections for the Patient Onboarding Team, working closely with cross functional colleagues including the US Com Marketing Team, SFE and Analytics Teams, OEC, Finance, the HCP and Government Sales Teams and Senior Leadership.
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Process Engineering, a part of AbbVie R&Ds Small Molecule CMC Development organization, is responsible for designing and developing scalable processes to make small molecule drug substances and drug products, including antibody drug conjugates (ADCs), throughout pre-clinical and clinical development stages.
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Perform a variety of cellular and molecular techniques (e.g., Western blot, Immunofluorescence, flow cytometry, CRISPR genetic editing) BS degree or master's degree in biological sciences, molecular biology, neuroscience, or biochemistry and significant 5+ years tissue culture experience are a must.
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BS degree with 0-5 years equivalent experience; M.Sc. with 0 - 2 years equivalent experience in biochemistry, molecular biology, chemical biology, bioanalytical chemistry or related areas. A B.S. or M.S. in biochemistry, chemical biology, molecular or cell biology, or analytical chemistry is desired.
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Skills & Abilities: Extensive scientific HLA knowledge and technical skills in the following areas preferred: HLA serology and molecular genetics, including NGS, platelet serology, HLA antibody screening /identification, Flow Cytometry Crossmatch, chimerism study, etc.
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Bachelor's degree in lab sciences such as Chemistry, Biochemistry, Material Science, Immunology, Biology, Molecular Biology or similar. Analytical characterization and assessment of clinical trial supplies (e.g. GMP compliant stability and release testing for both drug substances and drug products.
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Hands-on experience with one or more current LC-MS/MS platforms (e.g., Sciex Triple Quads, Agilent HPLCs, Shimadzu HPLCs, LEAP autosamplers, ADDA) and software (e.g., Analyst, Discovery Quant, Leadscape, Electronic Laboratory Notebook.
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molecular drug discovery jobs Title: post doctoral fellow Company: Emory University in North Chicago, IL
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