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Proficiency in standard molecular and cellular laboratory techniques such as flow cytometry, CRISPR, single-cell RNAseq, ELISA, Western Blot, primary cell culture. Proficiency in standard molecular and cellular laboratory techniques such as flow cytometry, CRISPR, single-cell RNAseq, ELISA, Western Blot, primary cell culture.
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This is a once-in-a-lifetime Global Expat leadership opportunity within the World’s Largest biologics CMO expanding to 620,000L total mammalian cell culture manufacturing capacity with commercial monoclonal antibody, mRNA vaccine and ADC manufacturing capabilities.
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Expertise in molecular biology techniques such as cellular engineering (i.e. transient transfection, lentiviral transduction, RNAi, CRISPRi/a), western blots, and ELISA. Develop and perform in-vitro cell-based assays to characterize antibody candidates; enable lead selection and candidate mechanism of action studies.
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Uses molecular and biochemical methods, including RNA isolation, qPCR, ELISA, WB. Experience in tissue sectioning, histology and microscopy is a plus. RNextraction, qPCR, ELISA (Nice to have: Western blot, IHC (including imaging and quantitation.
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Extensive experience with formulation development, Drug Product process development, and clinical in-use evaluation for monoclonal antibodies, bispecifics, antibody-drug conjugates, fusion proteins, and other complex biologics formats; experience of IND filings.
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Experience with cell-based assays, ELISA, MSD, qPCR, RNseq, microscopy, histology/pathology (e.g. IF/IHC/ISH), and/or flowcytometry. PhD Endocrinology, Physiology, Diabetes/Obesity, Immunology / Inflammation, or Metabolic Disease, or related biological science (MSc/BSs with relevant years of experience.
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GenScript ProBio is the subsidiary of GenScript Biotech Corporation, proactively providing end-to-end CDMO service from drug discovery to commercialization with proactive strategies, professional solutions and efficient processes in cell and gene therapy (CGT), vaccine, biologics discovery and antibody protein drug to accelerate drug development for customers.
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The Company's lead development candidate, DR-01, induces antibody-mediatedkilling of a specific cell type known to play a key role in various hematologic malignanciesand autoimmune disorders. Overall responsibilities will include oversight of clinical data managementactivities from study start-up through study closure in support of trial objectives andcorporate goals.
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Reporting to the Oncology Discovery Therapeutic Area head, you will partner with data science and machine learning (DSML), translational oncology and computational biology colleagues to gain deep insights into the biology and efficacy of antibody drug conjugates (ADCs) with the goal of delivering therapeutics to the right patients.
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Hands-on experience in laboratory techniques including mammalian cell line culture, siRNA/DNA transfection, genome editing, qRT-PCR, ELISA and western blot. Associate Scientist-Immuno-Oncology Research page is loaded.
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Experience with DLS/SLS, CE, ITC, MS, SEC-MALS, ELISA, Flow cytometry, and other analytical methods. Ph. D., M.S., or B.S. degree in a relevant scientific discipline (e.g. antibody/protein engineering, antibody discovery, bioanalytics) with appropriate industry work experience.
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Experience in molecular and cellular biology techniques, including but not limited to ELISA based assays, Proquantum, Luminex and ddPCR. Proficiency in multi-parameter flow and/or spectral cytometry including panel design, sample preparation and acquisition, antibody titration and data analysis.
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Prepare and analyze antibody/ADC samples for routine testing on analytical instruments such as RP-HPLC, SEC, LCMS (High Resolution and QQQ) This includes performing characterizations of antibody and ADC candidate molecules (routine QC, developability assessments, and peptide mapping.
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This role will support chromatography assay development for monoclonal antibodies, bispecific antibodies, cytokines, and antibody drug conjugates. This role will support chromatography assay development for monoclonal antibodies, bispecific antibodies, cytokines, and antibody drug conjugates.
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Lead preclinical validation of prioritized ADC antibody-linker-warhead combinations in cells and tumor models. Lead preclinical validation of prioritized ADC antibody-linker-warhead combinations in cells and tumor models.
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antibody elisa jobs in South San Francisco, CA
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