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This position will focus on antibody manufacture including upstream and downstream process development. We are seeking a Principal Scientist/Associate Director Antibody Process Development to join the Adcentrx CMC team.
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Familiarity with mass spectroscopy (MS) methods used for assessing mAb chemical stability and assessing ADC drug to antibody ratios including intact, reduced, and peptide mapping LC/MS. Avidity Biosciences, Inc.'s mission is to profoundly improve people's lives by delivering a new class of RNA therapeutics - Antibody Oligonucleotide Conjugates (AOCs.
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Accountable for assay development, validation and analysis of clinical biomarker data by collaborating with internal stakeholders and external CROs. Avidity is revolutionizing the field of RNA with its proprietary AOCs, which are designed to combine the specificity of monoclonal antibodies with the precision of oligonucleotide therapies to address targets and diseases previously unreachable with existing RNA therapies.
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In addition to gene therapy work, this role may include contributions to monoclonal antibody and peptide projects from inception to IND-enabling studies. Knowledge of protein structure function relationships and ability to apply protein engineering principles to antibody drug design is also highly desirable.
$150,700 - $218,500 a yearFull-timeExpandUpdated Today - UpvoteDownvoteShare Job
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Extensive knowledge of technical aspects of antibody process development, analytical development and manufacturing. The candidate will be responsible for leading the overall antibody development strategy from preclinical to GMP. Strategic, cross-functional leadership is a must.
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This position is a key member of the development team, executing clinical drug development activities by evaluating the clinical pharmacology of antibody therapeutics in an excellent organization that focused primarily, but not exclusively, on immune-inflammatory diseases.
$150,000 - $190,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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We excel in the rapid and efficient delivery of molecularly diverse therapeutic antibody candidates, well-characterized for function, kinetics, and developability, with expanding capabilities for engineering advanced modalities, including multispecifics and CARs. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science.
Full-timeExpandApply NowActive JobUpdated 3 months ago - UpvoteDownvoteShare Job
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We are currently seeking a self-motivated, collaborative Machine Learning Scientist to drive ML/AI powered protein design for next-generation biologics, including antibody, protein, peptide and beyond.
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Design and implement in vivo studies using rodent models to evaluate the pharmacokinetics, pharmacodynamics, and therapeutic efficacy of antibody candidates. Ph. D. in Pharmacology, Molecular Biology, Immunology, or a related field, with a strong focus on antibody therapeutics.
Full-timeExpandApply NowActive JobUpdated 20 days ago - UpvoteDownvoteShare Job
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Experience with super-resolution imaging techniques, microscopy, cell sorting, antibody based assays, biological sample preparation, image acquisition and data analysis, and/or cell based assay development.
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The core platform technology comprises proprietary targeted lipid nanoparticles (tLNPs) that are composed of LNPs conjugated with a recombinant protein binder, such as a monoclonal antibody. High-Performance Liquid Chromatography (HPLC), Liquid Chromatography Mass Spectrometry (LCMS), Fragment Analyzer, Capillary Electrophoresis.
$65,000 - $90,000 a yearExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Antibody screening utilizing ELISA, flow cytometry, and cell-based functional assays. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team’s experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab® Mouse platforms, ensure the highest probability of success.
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Experience with diverse purification approaches for different antibody formats, analytical characterization (SEC-HPLC, cGE, mass spec, cIEF, SEC-MALS), and developability assessment (thermal stability, poly specificity, hydrophobicity, forced degradation, serum stability) is required.
$158,500 - $192,900 a yearFull-timeExpandApply NowActive JobUpdated 2 months ago - UpvoteDownvoteShare Job
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Strong working knowledge of cellular immunology and molecular biology, including autoimmune and inflammatory diseases, with an applied understanding of antibodies, antibody generation, optimization and characterization, and broad biologics drug discovery research.
Full-timeExpandApply NowActive JobUpdated 3 days ago - UpvoteDownvoteShare Job
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Perform low and high-throughput screens using the Biacore 8K SPR for hit discovery, medicinal chemistry SAR support, and detailed evaluations of protein-antibody and protein-peptide interactions.
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antibody job in San Diego, CA
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