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Requirements include technical proficiency in general laboratory practices with an emphasis on protein biochemistry and molecular biology experience. Primary lab functions include protein expression, protein purification on a high-throughput platform, and molecular cloning.
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The Yang Lab in the Department of Microbiology & Immunology at Stanford University School of Medicine is currently recruiting for an experienced protein biochemist to join our lab as a Basic Life Research Scientist and work with a team of medicinal chemists, virologists, and structural biologists in developing novel small molecule antivirals.
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The successful candidate will apply state-of-the-art synthetic biology and cell engineering techniques to create research cell lines for recombinant protein production to support drug candidate screening in vitro and in vivo across Gilead’s therapeutic areas including Virology, Oncology, and Inflammation.
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Summary: Vaxcyte is looking for a highly skilled, motivated, and talented analytical scientist to join Vaxcyte’s Vaccine Product Development organization as Senior Associate Scientist within Protein Development and Clinical Manufacturing.
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Conducting analysis of these formulations using a broad range of standard protein biochemistry analytical techniques for formulation selection. The candidate will also have industry based experience in a range of standard protein biochemistry analytical techniques.
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Senior Research Associate/Associate Scientist, Protein Biochemistry Allakos Inc. is a clinical-stage company developing therapeutic antibodies for inhibitory receptors on the surface of immune effector cells involved in allergic, inflammatory and proliferative diseases.
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Using High Performance Liquid Chromatography (HPLC) to measure protein levels, including post-translational modifications and abundance levels. Using Polyacrylamide Gel Electrophoresis (PAGE) or proteomics using mass spectrometry to detect proteins and protein modifications.
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The Biologics group is responsible for various functions criticalfor drug development such as: antibody discovery, molecular biology, cell line engineering,protein engineering, biophysical analytics, and functional cell assays.
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The research can involve a variety of approaches including genetics, proteomics, mass spectrometry, protein engineering, and chemical biology. Possible research projects include investigations of the brassinosteroid signaling network, the O-glycosylation (O-GlcNAc and O-fucose) network, the crosstalk between nutrient-sensing O-glycosylation (O-GlcNAc and O-fucose) and hormone-regulated phosphorylation, and the functions of these signaling mechanisms in regulating cellular processes such as transcription, protein translation, protein degradation, vesicle trafficking, and cell division.
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Using molecular cloning and/or CRISPR techniques, generate plants with modified gene activity or expressing specific protein reporters. The team member will be an integral member of our team whose responsibilities will be to provide general lab support to the team (50%) and to work directly with a postdoctoral scholar to create and analyze new transgenics that allow us to monitor gene and protein activity in live, developing tissues.
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Ph. D in protein engineering, molecular biology, bioengineering, biochemistry, biotechnology, or related fields. Previous experience to design and execute protein engineering methods such as rational design and directed evolution.
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The successful candidate will have deep understanding of liquid and lyophilized formulation development for biologics, protein degradation pathways, biophysical characterization studies, drug product process development, tech transfer, process characterization, risk assessment and implementation of control strategies.
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Research Associate Protein Sciences. We seek a motivated and collaborative team member with molecular cloning, protein expression, purification, and characterization experience to join our Redwood Shore site's Discovery Protein Science group.
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Extensive expertise in U/HPLC, CE, SDS-PAGE, mass spectrometry, and other analytical technologies as applied to protein analytical method development, trouble shooting and validation for GMP release and stability testing.
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The successful candidate will be an integral member of the DST research team and work closely with various Research functions such as medicinal chemistry, structural biology and protein therapeutics to advance transformational therapies into clinical development for patients.
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protein job Title: post doctoral associate Company: University Of Minnesota in San Carlos, CA
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