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Demonstrated scientific acumen and mechanistic understanding of disease biology and experience in oncology and immuno-oncology drug development (biologics and cell therapies). This role involves designing and executing translational plans from program inception through pharmacodynamic mechanisms of action, target engagement, and patient selection assays and strategies, aligning with clinical development objectives for biologics (ADC or antibody) or cell therapy trials.
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Selection and application of appropriate purification techniques for biologics (i.e., SEC, hydrophobic interaction chromatography, ion exchange chromatography) Nice to have skills: Biologics analytic experience, purification techniques.
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8+ years of hands-on technical experience in biologics manufacturing or development (e.g., process development, cGMP manufacturing, process registration, analytical science), preferably in viral vector production, preferred.
$198,000 a yearFull-timeExpandUpdated Today - UpvoteDownvoteShare Job
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Knowledge of basic GMPs and regulatory requirements applicable to cell and gene therapy and biologics. Strong familiarity working in support of biologics or cell/gene therapy manufacturing processes and technology is a plus.
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My client is a leading bioanalytical and toxicology contract research organization (CRO) specializing in small molecule, biologics, and cell and gene therapy services. Strong understanding of bioanalytical and toxicology services, with experience in small molecule, biologics, and cell and gene therapy.
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Catalent Biologics Emeryville, CA site, formerly the startup company Redwood Bioscience, has developed a proprietary approach for site-specific bioconjugation to produce next-generation antibody-drug conjugates (ADCs.
$110,000 a yearFull-timeExpandUpdated Today - UpvoteDownvoteShare Job
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Reporting to VP of CMC Ops, the Director of CMC Operations is responsible for drug substance development and manufacturing in support of clinical development and commercialization of 89bio’s biologics pipeline drugs.
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Catalent Biologics Emeryville, CA site, formerly the startup company Redwood Bioscience, has developed a proprietary approach for site-specific bioconjugation to produce next-generation ADCs. This technology, termed SMARTag�, is based on use of the aldehyde-tag site-specific protein modification technology and Catalent's Client conjugation chemistry and proprietary, stable linkers.
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The Scientist IV, Analytical Development, Biologics CMC will independently conduct laboratory experiments with limited supervision to build in-house R&D testing capabilities in support of CMC analytical development projects for multiple types of biologics, including but not limited to antibody-drug conjugates (ADCs), monoclonal antibodies (mAb), and bispecifics (BsAb.
$141,500 a yearFull-timeExpandUpdated Today - UpvoteDownvoteShare Job
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Biologics Emeryville, CA site, formerly the startup company Redwood Bioscience, has developed a proprietary approach for site-specific bioconjugation to produce next-generation ADCs. This technology, termed SMARTag®, is based on use of the aldehyde-tag site-specific protein modification technology and.
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Hands on experience with conjugation, purification and characterization of antibody drug conjugates, and experience using analytical techniques/instrumentation, including chromatographic techniques such as HIC (Hydrophobic Interaction Chromatography) and RP (Reverse Phase), SEC, SDS-PAGE, UVVis.
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Must have: Bio-conjugation experience, protein biochemistry and Chemistry background. Immediate need for a talented Translational Research Scientist - I (Assistant). Minimum qualifications include a B.S./M.S/ PHD in chemistry, biochemistry, or related field, with industrial or academic experience.
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Experience with CMC regulatory considerations for late stage and/or commercial large molecules (biologics) is required experience with combination products is a plus. Manage CMC regulatory changes throughout the product life cycle, including support for relevant quality systems related to change control, discrepancy management, as well as Health Authority inspection support as required.
$329,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Significant contributions to successful biologics drug discovery programs in biotech/biopharma industry. Generate antibody fragment libraries for antibody discovery and engineering, perform HT binding screens (ELISA and multi-plex flow cytometry) and sequence analysis to generate hits.
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Reporting to the CSO, you will lead a team of drug discovery professionals in areas including: medicinal chemistry; DNencoded chemical library design, synthesis and screening; complex biologics (including antibody-drug conjugates, ADCs); oligonucleotides; analytical sciences; PKDM; protein sciences and structural biology.
$360,000 a yearFull-timeExpandUpdated Today
biologics job in Oakland, CA
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