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May perform fermentation, pDNA linearization, IT reactions, tangential flow filtration and chromatography, using a variety of equipment, including 3L or 30L bioreactors, spectrum TFF systems and AKTA HPLCs.
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Preferred Skills: Experience in growing and analyzing complex cultures of yeast, bacteria, and/or enzymes; well-developed palate that is able to make distinctions among flavors, ingredients, fermentation characteristics, and aging/storage methods.
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The successful candidate will play a key role in advancing our understanding of plant cell culture processes, with a focus on molecular and cellular biology, genetics, and plant cell culture fermentation.
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Collaborate with cross-functional teams to optimize upstream bioprocess parameters, such as pH, temperature, agitation, and aeration to maximize yield, productivity, and product quality to support exosome production.
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Experience with microbial fermentation at the plate and bench scale in bacteria and yeast. Strong scientific foundation in the understanding and implementation of a wide range of biochemical and cell-based assay readouts for small molecule production such as HPLC, LCMS, GCMS, fluorescence Polarization, Luminescence & Fluorescence-based reporters.
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Experience developing cell-free or fermentation processes is welcomed. Experience in several of the following areas: design of enzymatic activity assays, protein engineering, strain engineering, process development, high-throughput screening workflows and automation, enzyme discovery, biocatalytic retrosynthesis, bioinformatics, mechanistic enzymology, and computational protein design.
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Established capability to design, conduct, optimize and execute on novel biochemical and cell-based assay development efforts in the lab supporting HTS and project deliverables. Familiarity with software and statistical platforms for the analysis of large data sets (e.g., JMP, Tableau, Spotfire, or MODDE pro/DoE) is desirable.
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The advanced bio & physical sciences for low carbon energy team is the central research organisation for biosciences, chemistry, materials sciences, fundamental biofuels pathways, green hydrogen/ electrochemistry, and the science of carbon capture.
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Operate and maintain bioreactor systems and other fermentation equipment. Ph. D. or M.S. in Biology, Microbiology, Chemical Engineering, or related field with a minimum of five-year industrial experience in running fermentation processes for small molecule production.
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Expert knowledge and understanding of analytical chemistry, bioanalysis, and a thorough understanding of bioprocess as well as formulation development. Lead analytical development activities for the characterization of antibodies and/or synthetic peptides utilizing HPLC, LC-MS, Capillary Electrophoresis, peptide mapping, Mass Spectrometry, SDS-PAGE, ELISA, gel electrophoresis and modern glycoprotein & carbohydrate characterization techniques.
$166,700 - $241,325 a yearFull-timeExpandApply NowActive JobUpdated 19 days ago
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