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Role: seeking motivated, team-oriented individuals with expertise in protein purification process development to support our pre-pivotal purification & pilot operations group - an opportunity to work in teams for the early and late stage development of protein molecules.
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Incyte Corporation is seeking a motivated and experienced protein purification scientist to provide technical expertise in monoclonal antibody (including bispecifics) purification process development, characterization, and validation primarily for novel therapeutic monoclonal antibody products throughout all stages of clinical trials and commercialization.
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Successful candidate as a protein purification associate plays an integral role in the success of recombinant protein development and manufacturing. Perform protein purification methods on gravity or AKTA HPLC/ FPLC using affinity, ion exchange, hydrophobic, reverse-phase, and size exclusion chromatography.
$26.44 - $31.25 an hourFull-timeExpandApply NowActive JobUpdated Yesterday - UpvoteDownvoteShare Job
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Routine protein purification, including but not limited to:FPLC operation for routine FPLC purification processes (Affinity, SEC, CEX, AEX, HIC). Experience and core knowledge of protein production and purification is preferred.
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Job Title: Research Associate II – Downstream Process Development. Familiar with the downstream purification process, which includes centrifugation, chromatography, and filtration.
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We have up to two openings for an Academic Graduate Appointee participating in developing novel approaches and platforms in support of synthetic biology research emphasizing cell-free protein production methodologies and vaccine development.
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Expertise and knowledge in process development, scale up of formulation production and purification unit operations and tech transfer activities. Senior Scientist/Principal Scientist, Formulation & Process Development.
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Previous experience in small molecule drug discovery, specifically biochemical assay development and characterization of small molecule inhibitors and protein-ligand binding interactions.
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Perform protein purification, QC, and protein bank registration to support the preclinical development of biopharmaceutical programs across multiple therapeutic areas. Top 3 Nice to Have Skill Sets: Protein purification, Protein characterization, working knowledge of AKTA Avant/PURE.
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Understand all aspects of purification process development, process scale up - TFF (Tangential flow filtration), Chromatography. Requires 2+ years of experience demonstrating experience in purification process development (do not submit candidates with more than 5 years of this type of experience.
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Solid working knowledge of various manufacturing platforms (Microbial fermentation process, IB recovery and refolding, CHO cell culture and purification, Pegylation, PEGylated protein purification etc.
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Protein purification techniques: Experience in purifying recombinant proteins to high homogeneity for immunization purposes. Transient mammalian expression and protein purification.
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This role will also partially support activities in the Purification Process Development lab (15-20%). This role will be expected to independently execute cell culture process from harvest to final fill and to be cross trained in Downstream purification processes.
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Experience with ELISA, antibody/antigen selection and conjugation, protein purification, SDS-PAGE, Western blot, etc. The Research Associate I will support immunodiagnostic assay development following the product development process.
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Seeking motivated, team-oriented individuals with expertise in protein purification process development to support our pre-pivotal purification & pilot operations group - an opportunity to work in teams for the early and late stage development of protein molecules.
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process development protein purification jobs Company: Abbvie
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