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Broad experience in analytical techniques used to interrogate ex-vivo cell therapies (CART) and LVV, including but not limited to; molecular techniques (ddPCR, qPCR, NGS), flow cytometry, cell-based methods (bioassays, luciferase-based reporter systems, killing assays), imaging techniques.
$170,000 - $205,000 a yearFull-timeExpandApply NowActive JobUpdated 11 days ago - UpvoteDownvoteShare Job
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Broad experience in biochemistry, flow cytometry, molecular biology, in vitro and ex-vivo assays are essential. Independent scientists with a strong command of neuroscience-based in vivo and ex-vivo techniques, metabolism, molecular biology and biochemistry to contribute to target discovery, validation and preclinical development for novel therapeutics are encouraged to apply.
$51Full-timeExpandApply NowActive JobUpdated 5 days ago - UpvoteDownvoteShare Job
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Principal Investigator of Immunology, Therapeutics, Large Molecule, Flow Cytometry, In Vivo, In Vitro, Western Blot, ELISA, PCR, Research, Science, Comprehensive Benefits Package, Health, Vis, Dental.
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Proficiency in standard laboratory techniques, cell culture, and in vivo mouse studies. Conduct in vitro and in vivo experiments to evaluate the immunostimulatory properties of nanostructures.
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Boehringer Ingelheim is seeking an enthusiastic, creative, and highly motivated Postdoctoral Fellow to join the In Vivo Pharmacology Group in Cancer Immunology and Immune Modulation Department at our US headquarters in Ridgefield, CT. The Ridgefield campus, along with our sister sites in Texas and California, includes a thriving community of postdocs and PhD students that connects globally with their peers on our European campuses.
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Additionally, the specialist will assist with next-generation sequencing, cell culture, and the development and implementation of high-quality polychromatic flow cytometry and T cell-based assays.
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Experience in mouse ex-vivo work, immune cell culture, and advanced flow cytometry and cell culture techniques. Perform pharmacokinetic and pharmacodynamic (PK/PD) assays for in vivo models.
$97,400Full-timeExpandApply NowActive JobUpdated 5 days ago - UpvoteDownvoteShare Job
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Techniques include: high parameter flow cytometry (up to 27 colors), in vivo mouse work, fluorescent microscopy, confocal microscopy, standard tissue culture, standard mouse handling techniques, ELISA, ELISpot, 10x genomics, single cell PCR.
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High level of proficiency in mammalian cell culture (transfection, gDNA harvest, cell line generation), flow cytometry, and high throughput workflows. Scribe Therapeutics is a molecular engineering company focused on creating best-in-class in vivo therapies that permanently treat the underlying cause of disease.
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Experience in multi-color flow cytometry. Independently design, troubleshoot, and execute in vitro and ex vivo assays to narrow down promising hits from large antibody panels. A major focus will be on planning and execution of in vivo assays to generate proof of concept data.
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Experience with in vitro cellular biology/immunology assays applied to physiologically relevant human cellular models, flow cytometry, multiplex cytokine measurements, activation and cytotoxicity assays, micro-physiological systems, 3D organoids, membrane protein arrays, omics technologies, confocal imaging.
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A successful candidate will have had experience with preclinical drug discovery including immunoassays, flow cytometry, cell cytotoxicity assays, and ex vivo cell-based assays. Experience with multiparameter flow cytometry and cell-based assays (including cell cytotoxicity assays.
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Training in relevant cell therapy, stem cells, CAR-T cells, cell culture, flow cytometry and cryogenics preferred. In addition, will develop new processes and procedures including in-house generation of CAR-T cells, ex vivo NK cell expansion, and other new processes and procedures as deemed necessary by the Clinical Program Director and Medical Director.
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Relevant experience with T cells and other immune cells in vitro and in vivo, immunological techniques, and multicolor flow cytometry are highly desirable. Qualifications Candidates with a recent PhD or MD/PhD in immunology and experience in murine and/or human T-cell immunology, molecular biology, and in vivo modeling are encouraged to apply.
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Methods will include tissue culture, flow cytometry, single cell and spatial transcriptomics, droplet-based technologies, and genetic perturbation using CRISPR. This position is ideal for highly motivated applicants who are looking for an opportunity to further develop their wet and dry lab skills, gain knowledge in immunology, tumor biology, gene editing, single cell and spatial technologies, and aim to eventually drive their own independent research projects.
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