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We are seeking a highly motivated, energetic Research Specialist with some prior experience in biomedical research to work in a human pluripotent stem cell lab. Requires sophisticated experience with laboratory techniques in human stem cell biology and cellular and molecular biology.
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Training in relevant cell therapy, stem cells, CAR-T cells, cell culture, flow cytometry and cryogenics preferred. In addition, will develop new processes and procedures including in-house generation of CAR-T cells, ex vivo NK cell expansion, and other new processes and procedures as deemed necessary by the Clinical Program Director and Medical Director.
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Department BSD PED - Hematology, Oncology, and Stem Cell Transplantation - Piunti LabAbout the Department The Section of Pediatric Hematology/Oncology provides care for patients and families with acute and chronic medical conditions, or other hematologic diseases, requiring the specialty knowledge and skills of Hematology, Oncology and Stem Cell Transplantation.
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Stem cell related research experience including long term culture maintenance also highly desired. Experience with neural cell culture and/or stem cells highly desired.
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In addition to basic methods of cell and molecular biology including signal transduction pathways, microRNA and long noncoding RNA, transgenics and gene knock out the Chen Lab has used a number of rodent animal models, in which stem cells, growth factors and advanced matrix scaffolds are applied.
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This job entails developing induced pluripotent stem cell (iPSC) models of disease and differentiating these into neural progenitor cells (NPCs) and mature neurons to serve as reporters on markers of Alzheimer's and other diseases.
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Stem cell culture experience and/or flow cytometry experience is extremely desirable. They are used in drug discovery, toxicity testing, stem cell banking, and cell therapy development.
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Areas of expertise include genomics, epigenetics, drug resistance, stem cell biology, drug discovery, diagnostics and biomarker development, and pharmacology. Required technical skills include: RNA and DNA extraction, tissue culture, and flow cytometry techniques.
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Duties include creating specialized media formulation and maintaining an inventory of stem cell reagents and stock chemicals; preparing specialized culturing surfaces and maintaining a well-organized inventory of cell lines stored in liquid nitrogen; and routine stem cell core maintenance.
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The ideal candidate will have experience with mouse models and/or mammalian cell culture, particularly human embryonic/pluripotent stem cell culture. Experience with mouse models and/or mammalian cell culture, particularly human embryonic/pluripotent stem cell culture.
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Stem cell-based cell culture work. The Sr. Research Associate's objectives include conducting stem cell-based experiments and general lab maintenance in vision research.
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Astellas Institute of Regenerative Medicine (AIRM ) is a wholly-owned subsidiary of Astellas Pharma Inc and focused on the development and commercialization of stem cell and regenerative medicine therapies.
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Determine functionality of differentiated renal tissues both in vitro and in vivo using the knowledge of kidney tissue engineering and human stem cell culture. Develop protocols to differentiate renal tissue using the knowledge of kidney tissue engineering and human stem cell culture.
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Mammalian cell culture, stem cell, molecular biology, DNA, RNA, in vivo, iPSC s. 3+ years of hands-on experience with growth and maintenance of mammalian cell cultures using aseptic techniques.
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UMN MS is led by Dean and Vice President for Clinical Affairs Jakub Tolar, MD, PhD. Dr. Tolar is an international expert in recessive dystrophic epidermolysis bullosa, and he maintains his research program on hematopoietic stem cell transplantation as a treatment for rare genetic diseases.
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