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Cancer pharmacology, translational research, drug discovery, drug development. Ph. D. in pharmacology, oncology, cell biology, or a related discipline, with 2-5 years of post-doctoral and at least 8-10 years of relevant industry experience in cancer drug discovery and development.
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You will work with experienced pharmacometricians, Preclinical Pharmacokinetics, Drug Metabolism, Toxicology, and Clinical Pharmacology colleagues to provide inputs to overall product development plans and to address research and development objectives and issues.
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Provide oversight for DMPK/clinical pharmacology related sample management activities including management of BA CROs. You will collaborate with your colleagues in Discovery DMPK, biology, preclinical safety, clinical development, clinical operations, translational medicine and biostatistics to deliver high-quality deliverables following selection of a development candidate through clinical proof-of-concept.
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Develop and implement the rare disease translational medicine strategy across the portfolio, including developing and communicating translational questions, hypotheses, recommendations regarding study design, endpoints (including novel endpoints), safety evaluation, dose, pharmacology and PD biomarkers.
ExpandApply NowActive JobUpdated 12 days ago - UpvoteDownvoteShare Job
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Understanding and application of pharmacology, chemistry and non-clinical toxicology to effectively inform the conduct of safety surveillanceAbility to thrive in a fast-paced environment while providing appropriate attention to detail.
ExpandApply NowActive JobUpdated 13 days ago - UpvoteDownvoteShare Job
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Experience in generating LNPs in a preclinical industrial and/or academic setting using state-of-the-art LNP manufacturing methods like advanced microfluidics, T-mixing, and tangential flow filtration (TFF) is preferred.
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This position requires familiarity and fluency with the objectives and methodologies of preclinical animal research related to evaluating the efficacy, pharmacology and safety of new therapeutics, medical devices, and drug delivery technologies, ideally including experience with nonhuman primate research.
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Prior in vitro assays and in vivo pharmacology experience is a big plus. We offer our clients comprehensive service platforms around target validation, plate-based pharmacology, hit identification and lead discovery, in vivo pharmacology, as well as other research and development services.
$112,860 - $158,100 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Bachelor's degree with 15 + years of scientific experience in preclinical toxicology will also be considered. Provide strategic contribution as the subject matter expert for GLP, non-GLP safety assessments, off-target risk assessment, and safety pharmacology studies supporting development and platform programs.
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MS in Pharmacokinetics, Pharmaceutical Sciences, Pharmacology, Chemistry, Biochemistry, or related field with a specific focus on PK and PK/PD modeling and simulation and 10+ years of Pharmaceutical/Biotech industry experience in conduct and/or oversight of late-stage Modeling and Simulation activities, including conduct or oversight of small molecule population pharmacokinetic analyses.
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The In Vivo Pharmacology team at Kite Pharma FosterCity is seeking a Research Scientist to join an established group, to lead the development and characterization of in vivo murine models and associated ex vivo analyses for multiple cell therapy programs to address specific problematics related to engineered human chimeric antigen receptor T cells (CAR T cells.
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An exciting opportunity is available for a Director to join the In Vivo Pharmacology & Biomarker Discovery team of the Institute of Medicine (IOM) at Altos Labs. We are seeking a highly experienced and talented Director of In Vivo Sciences to conceptualize and lead our in vivo preclinical research supporting portfolio progression.
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Perform preclinical pharmacology studies in rodents. Its service platform integrates preclinical studies with innovative animal models, CRISPR-based gene editing, and animal supplies, with the current focus on immuno-oncology and oncology.
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Design and execute preclinical studies to understand the pharmacokinetics (PK) and absorption, metabolism, distribution, and excretion (ADME) of drug candidates that support drug discovery, preclinical and clinical development.
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You will maintain expertise in regulatory requirements and preclinical safety approaches applied to Immuno-Oncology therapeutics and awareness of industry trends. PhD in immunology, cancer biology, cell biology, toxicology, pharmacology, or related field with experience preferably in industry or academic setting with a minimum of 3 years’ experience.
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