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Demonstrated expertise and knowledge in the drug discovery/development and manufacturing market (cell, gene therapy or, large molecules or, biologics) with understanding of the served and total markets available.
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At 1910 Genetics, we put computation at the heart of drug discovery, blending expertise in computational chemistry, structural biology, pharmacology, genetics, data science, and software engineering to develop drugs for previously undruggable targets.
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A minimum of 10 years of related pharmaceutical or biotechnology industry experience in clinical pharmacology, population PK, PK-PD modeling, DMPK, and/or pharmacometrics and a proven track record advancing programs through the drug development process, from discovery through IND to registration, informing data driven decisions on dose and schedule, making tough judgement calls where needed.
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Within Janssen R&D, the Therapeutics Discovery organization is continuing to build the key scientific expertise to bring ground-breaking new medicines to patients; we invest in medicinal chemistry, screening, and pharmacology, and in the computational and data science fields that inspire and inform them.
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PhD or PharmD in clinical pharmacology, pharmacometrics, or related discipline with at least 7-10 years' experience in the pharmaceutical and/or biotech industry. In-depth knowledge of drug metabolism, pharmacokinetics, biopharmaceutics, drug-drug interactions, and translational science.
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A strong understanding of both preclinical drug discovery and clinical translatability in oncologySuccessful track record running in vitro and in vivo biology/pharmacology functions to drive small molecule programs from target selection (hit chemistry) to clinical proof-of-conceptBreadth of experience across different types of targets and mechanisms of action: transcription factors, undruggable targets and major drivers in oncology.
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Build QSP models integrating biological, pharmacological, and physiological data to support drug development at all stages, from preclinical research to clinical trials and beyond, aiding in dose optimization, biomarker identification, safety and efficacy assessment, drug development decision-making, etc.
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The ECS Clinician will work with other functional disciplines as needed (e.g. Research Unit clinicians/Global Clinical Leads/Medical Monitors, Biostatistics, Clinical Pharmacology, Precision Medicine, and Digital Medicine.
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Ph. D. in toxicology, biology/pharmacology, with at least 10 years related experience with vaccines and other biologics. Experience specifically supporting drug discovery research and development from a toxicology standpoint.
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We can accomplish our mission by building deep expertise in large molecule end-to-end discovery such as Antibody discovery, protein engineering and optimization, molecular attribute characterization, target protein & expression sciences, and platform biology/in vitro pharmacology/assay development.
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The In Vivo Pathology (IVP) team within the Pathobiology department is seeking a research associate to contribute to histology and pathology workflows in support of pre-clinical in vivo pharmacology studies.
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Pharmacology (administration and interaction) Ability to administer pharmacological drugs as ordered and have understanding of medication before administering (classification, adverse effects, therapeutic actions, indications, drug interactions, onset, duration, etc.
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3-5 years drug safety or clinical safety experience. Two years clinical experience in a medical setting, demonstrate general medical and pharmacology knowledge. A clinical degree (e.g., RPh/PharmD, BSN, RN.
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QP2-IO team is part of the Global Clinical Development organization and has oversight over drug development aspects related to clinical pharmacology and pharmacometrics of oncology drugs from post-PCC to registration.
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Supporting Pfizer Oncology, you will be a senior scientific and strategic leader and a member of the Pharmacometrics and Systems Pharmacology Leadership Team. In this key role, you will influence the discovery and development of drugs and expand the application of model-informed drug development (MIDD) approaches within oncology and across our portfolio.
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