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Strong understanding of clinical pharmacology and pharmacometrics principles and the drug development process. This position is responsible for leading efficient, innovative population PK, PK/PD, exposure-response plan, analysis, interpretation, and reporting to support international drug development programs.
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The Toxicologist works in a team environment (toxicology, pharmacology, medical/clinical, regulatory, CMC) in Biotech drug discovery and development. In addition, the Toxicologist will liaise with discovery and development colleagues and participate in development of the overall toxicology and pharmacology strategies.
Part-timeExpandApply NowActive JobUpdated 4 days ago - UpvoteDownvoteShare Job
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You will work with experienced pharmacometricians, Preclinical Pharmacokinetics, Drug Metabolism, Toxicology, and Clinical Pharmacology colleagues to provide inputs to overall product development plans and to address research and development objectives and issues.
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Global Discovery and Development Sciences (GDDS) Boston, part of the US R&D hub, is building a new siRNA Nonclinical Development department with cross-functional scientific expertise, including toxicology, safety pharmacology, PKPD, ADME, outsourcing management, and non-clinical project management.
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Associate Director / Director of Clinical Pharmacology, Cardiovascular, Renal, And Metabolism (CVRM)
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At least 3+ years industry experience or equivalent in pharmacokinetics and clinical pharmacology aspects of drug development (position level depends on overall years of proven experience.
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Build QSP models integrating biological, pharmacological, and physiological data to support drug development at all stages, from preclinical research to clinical trials and beyond, aiding in dose optimization, biomarker identification, safety and efficacy assessment, drug development decision-making, etc.
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Provide in vitro biology and pharmacology support and collaborate with other drug discovery functions to advance preclinical programs and achieve company milestones. Experience in luminescence based and qPCR assay development, optimization, and high throughput screening in the context of small molecule drug discovery programs.
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This position reports to the head of clinical pharmacology and toxicology and liaises with clinical development, clinical operations, non-clinical pharmacology and toxicology, and drug discovery to execute activities for advancing the development pipeline.
$150,000 - $190,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Develop and implement new clinical pharmacology tools and technologies to drive efficient drug development. FibroGen recently expanded its research and development portfolio to include antibody-drug conjugate (ADC) and immuno-oncology product candidates for the treatment of solid tumors.
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Comprehensive understanding of drug development and related concepts, such as clinical trial design, statistics, and clinical pharmacology. Abdera Therapeutics Inc. is a precision oncology company developing next-generation targeted radiation therapies- one of the most cutting-edge and highly promising areas of drug development.
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Demonstrated success in managing clinical pharmacology activities and quantitative drug development (population PK, mechanistic PK/PD modeling/systems pharmacology, and clinical trial simulations.
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15 years of drug development experience including interactions with global Health Authorities; must include late-stage assets and interactions with global regulatory agencies for IND/CTA and NDA/BLA/MAA filings and application of this experience to pipeline projects and platforms.
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Collaboratively coordinates surveillance of drugs and therapeutic developments within drug treatments for critically ill patients for the core pharmacology database updates. Conducts peer review of content development (e.g., professional drug monographs, projects.
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Collaborate with internal/external experts in Clinical Development, Biostatistics, Clinical Pharmacology, Translational Medicine, Clinical Operations and Data Management to support clinical trial execution.
ExpandApply NowActive JobUpdated 16 days ago - UpvoteDownvoteShare Job
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PhD or equivalent degree in Pharmaceutical Sciences, Molecular Biology, Chemistry, Biochemistry or Pharmacology with experience in drug discovery, or a higher degree in a research area relevant to DMPK science.
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