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Develop other molecular biology-based assays using techniques such as cloning, DNA/RNA/protein extraction and RT-PCR. Responsible for designing and conducting research studies to support our drug discovery programs, including target validation, structure-activity relationship assessment, biomarker discovery, and mechanism of action studies.
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Basic understanding of protein chemistry, molecular biology and immunology. Carry out wet lab activities related to protein engineering and drug discovery. We provide support in molecular biology, protein production and purification, protein characterization, and in high-throughput protein optimization using directed evolution techniques.
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Our unique Antibody Biopolymer Conjugate (ABC) platform merges the fields of protein engineering and polymer chemistry and is at the core of our discovery engine. Perform varied cell and molecular biology techniques including cell culture, imaging, protein, and RNA analysis.
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This individual will collaborate with the Antibody Discovery, Protein Sciences, Vivarium, and Systems Engineering groups. The ideal candidate has experience in molecular genetics, design of complex constructs, and transgenic animals as well as knowledge of B cell development and mechanisms of antibody diversification.
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At the forefront of medical discovery as it relates to understanding the causes of obesity, diabetes, cardiovascular disease, cancer and dementia, Pennington Biomedical Research Center is a campus of Louisiana State University and conducts basic, clinical and population research.
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Research themes include health policy, technology uptake, quality of care, pharmacoepidemiology, novel drug discovery, androgen receptor biology, MR imaging in cancer staging, device development, inflammation, and molecular mechanisms of azoospermia.
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Our basic science and translational research domain expertise spans regenerative medicine, molecular medicine, biomaterials, molecular, cellular, tissue Engineering and biomedical micro/nano technology.
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Experience in therapeutic drug discovery, gene therapy or RNA therapeutics. Hands-on experience with cell-based assays and general molecular biology methods including, but not limited to, cell transfection, IVT, RNA extraction, qPCR, ddPCR, FACS, TapeStation, or Fragment Analyzer.
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The primary focus of the Associate Scientist role will be to support development and execution of molecular assays to support the preclinical development of CAR T assets working at the interface between process and analytical development.
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This Scientist should have a strong background in immunology and molecular biology mastery in isolating various primary cells such as different types of T and B cells familiarity with Luminex Multiplex assay and proficiency in Flow Cytometry.
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The faculty are internationally renowned for their strength in elucidating basic cellular and molecular mechanisms of signal transduction that lead to innovative drug target identification and ultimately to drug discovery.
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Experience in standard cellular and molecular biology techniques (Cell culture, ELISA, Cell-based assays, Immunofluorescence, Western blotting, Microscopy, RNA/DNA isolation, qPCR) Conduct/execute in vitro, ex vivo and/or in vivo studies to facilitate drug discovery and development with some independence.
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The incumbent will be responsible for drug screening, cell-based assay development, and biomarker discovery. Demonstrate proficiency with sterile cell culture, cell-based assays (CTG, apoptosis) and molecular.
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Apply knowledge of molecular biology, genetic engineering, and chemistry to peptide discovery and optimization activities for a given biological target of interest. Drug Hunting Focus: The candidate is expected to exhibit strong problem-solving abilities and be familiar with understanding and resolving issues that lie at the interface of peptide discovery, peptide engineering, pharmaceutical developability and formulation, and biology.
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Doctoral (PhD) degree in molecular biology, biochemistry, genetics, or an equivalent field. We are looking for a molecular biologist to join our fast-growing organization as a new addition to our NGS team.
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nih molecular discovery jobs Title: doctoral fellow
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