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The incumbent will use a variety of molecular, cell biology, and biochemical techniques under the direct supervision of the Principal Investigator to implement an NIH-funded research program.
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This individual will collaborate with the Antibody Discovery, Protein Sciences, Vivarium, and Systems Engineering groups. The ideal candidate has experience in molecular genetics, design of complex constructs, and transgenic animals as well as knowledge of B cell development and mechanisms of antibody diversification.
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Our unique Antibody Biopolymer Conjugate (ABC) platform merges the fields of protein engineering and polymer chemistry and is at the core of our discovery engine. Perform varied cell and molecular biology techniques including cell culture, imaging, protein, and RNA analysis.
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The ideal candidates will be proficient in molecular and cellular biological skills and have a passion for contributing to drug discovery. Demonstrated expertise with molecular biology techniques, “omic” technologies and cell culture is required; facility with mouse models and in vivo pharmacology is a plus.
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Research themes include health policy, technology uptake, quality of care, pharmacoepidemiology, novel drug discovery, androgen receptor biology, MR imaging in cancer staging, device development, inflammation, and molecular mechanisms of azoospermia.
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Apply knowledge of molecular biology, genetic engineering, and chemistry to peptide discovery and optimization activities for a given biological target of interest. Drug Hunting Focus: The candidate is expected to exhibit strong problem-solving abilities and be familiar with understanding and resolving issues that lie at the interface of peptide discovery, peptide engineering, pharmaceutical developability and formulation, and biology.
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Visterra, Inc., is seeking a highly motivated Research Associate with research experience in biochemistry, cellular and/or molecular biology to help discover and develop biologic therapeutics, as well as expand platform technologies that support our antibody-based drug discovery programs.
$78,000 - $83,500 a yearFull-timeExpandApply NowActive JobUpdated Yesterday - UpvoteDownvoteShare Job
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This drug discovery research position will support and collaborate with a research team to identify and validate disease-modifying molecular targets and support the progression of drug development projects to clinic.
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Successful candidates will interface with members among all areas of the WCNDD, including those in molecular pharmacology, medicinal chemistry, drug metabolism and pharmacokinetics, and in vivo rodent pharmacology.
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Chemistry is a core capability in Small Molecule & Drug Discovery with innovative scientists working in medicinal chemistry, radiochemistry, analytical chemistry, and large-scale synthesis. The Cheminformatics team within Bristol Myers Squibb is seeking an exceptional scientific leader interested in artificial intelligence and machine learning for molecular design.
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Experience in standard cellular and molecular biology techniques (Cell culture, ELISA, Cell-based assays, Immunofluorescence, Western blotting, Microscopy, RNA/DNA isolation, qPCR) Conduct/execute in vitro, ex vivo and/or in vivo studies to facilitate drug discovery and development with some independence.
$65,000 - $78,000Full-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Current working knowledge of cellular and molecular immunology, cell biology, or related discipline, with an applied understanding of antibodies and antibody generation, biologics drug discovery research and disease target evaluation.
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Stay abreast of the latest advances in molecular dynamics, protein degradation, and pharmaceutical discovery domains, and actively incorporate novel methodologies to enhance project outcomes.
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The research program presents the opportunity to utilize a variety ofapproaches including cell culture, molecular biology, protein chemistry,immunohistochemistry, flow cytometry, small animal surgery (rat and mouse modelsof middle cerebral artery occlusion, implantation of micro-pump , magneticresonance imaging (MRI) of rodent brains, as well as behavioral studies.
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Experience with microbiology of Gram-negative species, antibacterial development, genetics and molecular cloning to determine and develop target antigens, eukaryotic cell culture, expression vector design, transient transfection, recombinant antibody testing and development, protein expression.
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nih molecular discovery jobs Title: doctoral
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