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Manage the specification, design, manufacture, and qualification of custom and standard capital equipment used for pharmaceutical and biopharmaceutical product manufacturing (example equipment types include fermentation, chromatography, buffer formulation, synthetic organic chemistry.
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Manages the processing operations of cultured products facilities (cream cheese and/or yogurt) including separation (raw and pasteurized), formulations, blending, pasteurization, ultra-filtration and fermentation with responsibility for efficient utilization and coordination of raw and pasteurized materials.
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Possesses working knowledge in downstream processing for vaccine production, e.g. Lyophilization, Tangential Flow Filtration, Centrifugation, Emulsification, Filling, etc. Possesses working knowledge in vaccine antigen production processes, e.g. Tissue Culture, Fermentation, Chicken Embryo Origin Processes, etc.
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As a Biopharm Manufacturing Associate II, you will perform production operations including fermentation or cell culture operations, preparation of solutions, chromatographic separation, filtration and concentration operations, autoclave and parts washing of process assemblies, and area cleaning/upkeep.
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Upstream Manufacturing (UM): Primary focus is the cleaning, sterilization and operation of fixed vessel systems for media preparation, fermentation, and harvest operations; perform seed train operations; perform dispensing of components; handle and aliquot hazardous materials.
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Perform shake flask culture, cell banking, fermentation, harvest clarification, normal and tangential flow filtration, homogenization, conjugation, chromatography techniques and/or formulation as needed.
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Train and develop local and remote Leaders and hourly Partners on key processing unit operations including, but not limited to, centrifugal separation, ultra-filtration, homogenization, pasteurization, fermentation, and formulations.
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Experience with bioreactor, cell culture, microbial fermentation, and cGxP is preferred. Apply principles of biology, chemistry, and other scientific fields to design, execute, document, and present on small-scale experiments to improve process knowledge on cell culture, chromatographic, or filtration processes.
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Using a combination of scientific rigor, engineering fundamentals, and interpersonal skills, you will start up, stabilize, and continuously improve production at various precision fermentation DSP production sites.
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Tasks to be completed may include fermentation, protein purification, solvent extractions, tissue culture, preparation of bulk solutions, aseptic fills of buffers, filling and labeling of vials under sterile and non-sterile conditions, component preparation, filtration, vial preparation and sterilization.
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The ideal candidate will have in-depth of knowledge of principles and theories of cell line development, medium and feed development, cell culture processes, or bioseparations including chromatography, filtration, and precipitation.
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3rd shift hours: 9pm - 5:30 am (starts Sunday evening), Will train on 1st or 2nd shift. Aseptic manufacturing experience Minimum - HS diploma 90% working line Must have process experience/manufacturing process.
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Additional experience in downstream purification of biologics including chromatography separations and filtration operations (depth, dead-end, and ultrafiltration/diafiltration) is a plus. Our vaccine client in Boston, MA is looking to add a hands-on, Director, Bioprocess Development (Microbial/Fermentation) to their team.
$200,000 - $240,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Knowledge of biotechnology operations such as, Aseptic Filtration Systems, Fermentation Process, Inoculation Process, Chromatography Columns, TFF step etc. Fermentation and harvest.
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The successful candidate will work closely with members of the pilot plant and process development teams who are responsible for fermentation, downstream recovery and purification. Operation of centrifuge, Tangential Flow Filtration (TFF) and chromatography systems.
$30.53 - $41.11 an hourFull-timeExpandApply NowActive JobUpdated Yesterday
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