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The Protein Engineering Team works to address the complex challenges of enzyme discovery, characterization, and engineering. Model interpretation and application: Understand and predict the effects of sequence variation on protein function and biophysical parameters that are relevant for enzyme and protein engineering and improvement.
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Primary responsibilities may include buffer preparation, drug formulation, endotoxin testing, animal tissue processing, DNA/RNA/protein isolation, spectrophotometry, chromatography, immunochemistry, microscopy, image analysis, enzyme activity assays, protein/oligo/small molecule interaction techniques (ELISA, SPR, BLI, MST, FRET, etc), various molecular biology techniques (PCR, qPCR, ddPCR, dPCR, SDS-PAGE, etc.
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Use structural information, bioinformatics, molecular modeling, and / or machine learning techniques to develop protein sequence/structure/function relationships and make engineering recommendations for improving desired enzyme properties.
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Responsibilities include but not limit to: expression and purification of proteins/mutants, kinetics studies, and preparation of enzyme intermediates for spectroscopy studies. A strong background/experience in genetic code expansion, molecular biology and/or protein biochemistry is desirable.
$3,199.73 - $4,585.53 a monthExpandApply NowActive JobUpdated Yesterday - UpvoteDownvoteShare Job
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Biochemical techniques including quantitative Polymerase Chain Reaction (qPCR)/Digital Droplet PCR (ddPCR), Enzyme-Linked Immunosorbent Assay (ELISA), western blotting, gel-based assays, tissue culture, etc.
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Candidate must have a strong background in protein/enzyme research demonstrated by at least one first author publication in reputable journals. Research scientist or postdoctoral associate- Protein engineering.
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GenScript ProBio is the subsidiary of GenScript Biotech Corporation, proactively providing end-to-end CDMO service from drug discovery to commercialization with proactive strategies, professional solutions and efficient processes in cell and gene therapy (CGT), vaccine, biologics discovery and antibody protein drug to accelerate drug development for customers.
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Solid technical ability and hands-on experience with molecular biology, ribonucleic acid ( RNA) and protein analysis, analytical gel electrophoresis, quantitative polymerase chain reaction (qPCR),enzyme-linked immunosorbent assay (ELISA), western blot, flow cytometry, quantitative reverse transaction (qRT-PCR), microscopy, histology, and cell culture.
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Experience with enzyme, protein isolation, and mixing processes. ABF is a broad portfolio of businesses which includes Primark, Ovaltine, Twinings, AB Enzymes, and is a worldwide producer of both sugar and baker's yeast.
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The successful candidate will have hands-on experience with cell-based in-vitro potency assays, SDS-PAGE, Automated Western blot assays, enzyme activity measurements, protein extraction, purification, and quantification methods.
$72,000 - $90,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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GenScript's businesses encompass four major categories based on its leading gene synthesis technology, including operation as a Life Science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy.
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This includes understanding concepts such as protein structure and function, enzyme kinetics, molecular biology techniques, and cellular signaling pathways. Scientific Knowledge: A strong foundation in discovery sciences and protein biochemistry is essential.
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The Engineer/Scientist, Protein Development is responsible for research and process development in our enzyme program using conventional fermentation and purification methods. Minimum of 8 years working in a pharmaceutical or industrial protein process development laboratory or manufacturing sciences and technology labor, or equivalent role, in an industrial enzyme fermentation facility (min 10m3 fermenter volume.
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Our faculty members conduct research in areas such as drug discovery, medicinal chemistry & medical devices, cosmochemistry, prebiotic chemistry, archaeological science, computational chemistry, enzymology and enzyme mechanisms, RNA and protein chemistry, and polymer chemistry.
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Viral DNA, RNA and protein extraction, purification, and analysis, including cloning, amplification and DNA sequencing. Analysis of viral growth by microscopy and enzyme assays. Viral DNA, RNA and protein extraction, purification, and analysis, including cloning, amplification and DNA sequencing.
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