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We use high resolution electron cryo-microscopy (cryo-EM) and image processing to explore the molecular design of large, multicomponent supramolecular assemblies. A special advantage of this rapid-freezing method is that we can trap and image dynamic states of functioning macromolecular assemblies, such as open and closed states of membrane channels and viruses actively transcribing RNA. Three-dimensional density maps are obtained by digital image processing of the high-resolution electron micrographs.
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The successful incumbent will work as a cryo-electron microscopy (cryo-EM) specialist focused on deciphering the structural basis for neurodegenerative diseases, including Alzheimer's disease (AD), frontotemporal dementia (FTD), multiple system atrophy (MSA) and Parkinson's disease (PD.
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You will be joining a larger group which offer many opportunities for growth and development in other areas of preclinical and investigative safety including cross training to execute the in vivo aspects of preclinical studies, molecular pathology techniques, digital pathology, image analysis and electron microscopy.
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The MCW Cancer Center will soon relocate into a new facility, with investment in innovative technologies, including metabolomics, glycobiology, and cryo-electron microscopy, amongst others.
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Significant understanding and experience utilizing relevant catalyst physical and chemical characterization methods to accelerate development, including high resolution electron microscopy, X-ray diffraction, x-ray photoelectron spectroscopy, x-ray fluorescence, and high energy spectroscopic methods.
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The University of California, Irvine is currently accepting applications for a specialist position to manage the day-to-day operations of electron microscopy facilities and services to users at the UC Irvine Materials Research Institute (IMRI.
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Demonstrated working knowledge of analysis techniques, including but not limited to: Scanning electron microscopy, Scanning probe microscopy, Contact profilometry, 3-D optical profilometry, Film stress measurement, ellipsometry, interferometric microscopy.
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Ability to conduct metrology such as optical/infrared microscope inspections, interferometric measurements and scanning electron microscopy with elemental analysis and is required. Possesses experience and process development expertise in contact/stepper photolithography, wet and plasma dry etches, high aspect-ratio deep reactive ion etching (DRIE) of silicon, glass and other MEMS relevant materials, chemical vapor deposition, dielectric and metal depositions, wafer bonding and vacuum encapsulation of microscale structures, sacrificial and structural layer creation and wet/dry release.
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These range from optical microscopy to scanning electron microscopy and transmission electron microscopy. Team members are also involved with laser and electron beam additive manufacturing.
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Battery electrode analysis using optical, electron and X-ray microscopy. Familiar with Failure Analysis techniques such as Optical Microscopy, X-ray/CT, XRD, SEM, EDS, FIB, FTIR, GCMS etc.
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The Senior Research Associate will utilize scanning electron microscopy, dynamic light scattering, polymer synthesis protocols, and animal handling skills. Perform analysis of SEM, TEM, DLS, Western blotting, ELISA, DNA and RNA isolation, PCR, in vivo studies using animals.
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Surface and microstructure characterization using advanced techniques such as interferometry, white light interferometer, electron microscopy, surface profilometers, and analytical techniques.
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We are seeking a Software Engineer to work on developing backend infrastructure services to support the mapping of cells between the light and electron microscopy dataset. We are a dynamic multi-disciplinary team with deep expertise in electron and light microscopy reconstructions and contribute to innovative research in the field.
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Stains, electron microscopy), and provide interpretation. Performs autopsies, with or without an autopsy assistant by correlating of the gross pathology with the patient’s clinical presentation, preparation of external and internal descriptions.
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Hands-on electrical testing, nondestructive imaging (c-mode scanning acoustic microscopy (CSAM) and x-ray), chemical de-processing, cross section / polishing, fault location (hotspot thermal imaging), scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) to identify root cause of failure.
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