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Support antibody expression construct generation by molecular cloning, DNA sequencing, and plasmid DNA purification. Antibody characterization/QC by SDS-PAGE, HPLC-SEC, and Gator to determine antibody quantity and quality.
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This is a once-in-a-lifetime Global Expat leadership opportunity within the World’s Largest biologics CMO expanding to 620,000L total mammalian cell culture manufacturing capacity with commercial monoclonal antibody, mRNA vaccine and ADC manufacturing capabilities.
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Familiarity with mass spectroscopy (MS) methods used for assessing mAb chemical stability and assessing ADC drug to antibody ratios including intact, reduced, and peptide mapping LC/MS. Avidity Biosciences, Inc.'s mission is to profoundly improve people's lives by delivering a new class of RNA therapeutics - Antibody Oligonucleotide Conjugates (AOCs.
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The Associate Technician Production Operations for Beckman Coulter Diagnostics is responsible for following established procedures for in vivo antibody production and animal care in a regulated laboratory environment.
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Has hands on experience with executing antibody or antibody-like molecule purification techniques including resin chromatography (affinity, CEX, AEX, MMC), depth filtration, virus filtration, membrane chromatography, and TFF operations.
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By 2030, Genmab’s vision is to transform the lives of people with cancer and other serious diseases with Knock-Your-Socks-Off (KYSO) antibody medicines. To help develop and deliver novel antibody therapies to patients, Genmab has formed 20+ strategic partnerships with biotechnology and pharmaceutical companies.
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Experience carrying out retro-orbital bleeds and intravenous and intraperitoneal injections, isolation and preparation of mouse tissues for antibody staining, and analysis by flow cytometry. The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life.
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This will include formulation and commercial process development for biologics (monoclonal antibodies, antibody drug conjugates, bispecifics and fusion proteins). The Biologics Drug Product Development group develops monoclonal antibodies, antibody drug conjugates (ADC), and other biologics using state of the art formulation and process technologies.
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Skills & Abilities: Extensive scientific HLA knowledge and technical skills in the following areas preferred: HLA serology and molecular genetics, HLA antibody screening /identification of HLA antibody specificity, cross matching techniques to support stem cell transplantation programs and platelet transfusion therapy and other areas in the field of Histocompatibility and Immunogenetics.
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The Antibody Solutions Division of Fortis Life Sciences is comprised of three wholly owned subsidiaries: Bethyl Laboratories, Abcore, and Arista Biologicals, Inc. The Quality Systems Manager position will be based primarily on site at Bethyl Laboratories located in Montgomery, TX which specializes in custom monoclonal and polyclonal antibody production services that support scientific discovery.
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Mosaic teams provide comprehensive, end-to-end discovery services, including program assessment and strategy development; program management; antibody discovery and optimization; protein production, purification, and characterization; protein engineering; biochemical and cellular assay development; formulation, stability and developability studies; bioanalytical (PK and PD) assay development; and candidate-validating pharmacology.
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Associate Scientist, Antibody Discovery and Engineering. Develop and execute biochemical enzymatic assays, antibody screening, and binding assays. 1 year in molecular biology techniques with hands on expertise in DNA/RNA extraction, PCR, q-PCR, mutagenesis & assembly reactions, SDS-gel page, electrophoresis, cloning replication - pDNA techniques, western, northern, southern blotting, different cell line cultures, affinity chromatography, ELISA, microfluid liquid handling system, and thin layer chromatography.
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The position requires extensive experience in antibody-based therapeutics, protein engineering, molecular biology, purification, and characterization. Experience in therapeutic antibody engineering is required.
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Produce NGS amplicon libraries for antibody repertoire analysis. Clone and express recombinant antibodies in 293 cells and confirm antibody binding by ELISA. OmniAb provides our pharmaceutical industry partners access to the most diverse antibody repertoires and cutting-edge screening technologies to enable discovery of next-generation therapeutics.
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We have the capabilities to analyze virtually any peptide, protein, or antibody, and have built a reputation for solving technical challenges related to assay development and validation. The scientist will perform assigned projects and work closely with peers in Biologics group to perform routine Anti-drug Antibody (ADA) and Neutralizing Antibody (NAb) immunoassay bioanalysis in the support of clinical and non-clinical studies.
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