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The business includes our proprietary GPEx cell line engineering platform, our new state-of-the-art biomanufacturing facility in Madison, WI, and our market leading biologics analytical services as well as SMARTag Antibody Drug Conjugate technology in Emeryville, CA. Leveraging our growing differentiated technology portfolio, world class manufacturing capability, and other integrated services across the Catalent network, Catalent Biologics is positioned to drive significant growth for Catalent.
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Incubated in 82VS, Alloy Therapeutics' affiliated venture studio, Aakha Biologics was created through a collaborative partnership model that leverages access to Alloy's ATX-Gx transgenic mouse, suite of antibody discovery platforms, and discovery services.
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This role will support chromatography assay development for monoclonal antibodies, bispecific antibodies, cytokines, and antibody drug conjugates. PhD in analytical chemistry, biochemistry, molecular biology or related scientific field and 2+ years of industry experience in the characterization of large molecule biologics is required OR.
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As a scientist you will be responsible for the design and execution of in vitro display technologies for lead antibody identification/optimization and collaborating to generate stage-gate appropriate in vitro / cellular / in vivo data packages supporting PoC. The candidate will leverage expertise to develop and implement research to gain a mechanistic understanding of the molecular pharmacology of therapeutic molecules.
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The Therapeutics Discovery Division is organized around four platforms: The Institute for Applied Cancer Science (IACS), ORBIT (Oncology Research for Biologics and Immunotherapy Translation), TRACTION (Translational Research to Advance Therapeutics and Innovation in Oncology) and the Neurodegeneration Consortium (NDC.
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Strong understanding state-of-the-art methods and technologies used in the industry Tissue handling techniques for detection of gene and protein expression, including fixation, sectioning, IHC, histological staining, ISH MAbs/bi specifics - expertise in antibody protein structure & function, ability to apply protein engineering principles to mAb drug design.
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Essential for the rolePh. D. in Biotechnology, Molecular Biology, Biochemistry or other relevant scientific field with 5+ years of experience in antibody engineering and/or bispecific design. BUSINESS AREABiologics Engineering (BE) is large global organization with teams in Cambridge, UK and Gaithersburg MD responsible for the discovery and optimization of next generation biologics to create biological drug candidates for all key therapeutic areas such as oncology, respiratory and inflammation, cardiovascular, renal and metabolic diseases.
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Extensive experience with formulation development and tox/clinical in-use evaluation for monoclonal antibodies, bispecifics, antibody-drug conjugates, fusion proteins, and other complex biologics formats, in a wide concentration range from ultra low to high; experience of IND and/or BLA filings.
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Our preclinical pipeline extends beyond to biologics against novel immuno-oncology targets, antibody-drug conjugates, bispecific and trispecific antibodies, and small molecules expected to reach the clinic in 6-24 months, underscoring our bench-to-bedside approach.
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Who You Are: You are a dynamic Computational Scientist who will work with other scientists to apply cutting-edge computation, Machine Learning/Deep Learning approaches to revolutionize our large molecule computational tools by contributing to accelerating and improving the process of design and engineering of novel biologics drug candidates.
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The Vice Preside of CMC Radiopharmaceutical Process Development will provide oversights to cell line development, antibody process development and scale up, conjugation and radio drug substance and drug product development and GMP manufacturing.
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GenScript ProBio is the subsidiary of GenScript Biotech Corporation, proactively providing end-to-end CDMO service from drug discovery to commercialization with proactive strategies, professional solutions and efficient processes in cell and gene therapy (CGT), vaccine, biologics discovery and antibody protein drug to accelerate drug development for customers.
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GenScript's businesses encompass four major categories based on its leading gene synthesis technology, including operation as a Life Science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy.
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In terms of viral vector service, GenScript ProBio has a stable and high-yield viral vector platform. In terms of plasmid service, GenScript ProBio supports the most clinical approvals for CGT drugs including mRNA vaccines, CAR-T in China.
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The ideal candidate will be supporting biologics, antibody and new modalities. You have experience in Biologics or anti-bodies. Using program management knowledge and experience in the drug development industry, this team member would provide operational Project Management leadership to Preclinical Development (PCD) and Drug Safety & Pharmacometrics (DSP) on assigned projects with minimal guidance.
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