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- Position Overview: A Scientist or Senior Scientist to support the development of the Allogeneic Cell Therapy pipeline programs.
- The primary focus of the Attribute Sciences Scientist / Senior Scientist role will be to collaborate with Client team member to build in depth allogeneic CAR T cell product and manufacturing process data and understanding with particular focus on exploratory / investigational studies to support: The identification of drug product Critical Quality Attributes (CQA) to inform the overall product control strategy for the manufacturing of high quality, best in class allogeneic cell therapy products.
- Successful consultant will have a strong foundation in Immunology and human T cell biology and experience with the design, optimization, and implementation of a broad range of in vitro cell-based and / or molecular T cell characterization assays (i.e. cytotoxicity assays, proliferation, cytokine production assays, multi-color conventional and spectral flow cytometry, gene editing, transcriptome and proteome profiling, etc
- Prior research experience with T cells / CAR T cells (including cell therapy research, allogeneic hematopoietic stem cell transplantation, etc.)
- Design, optimize and execute in-depth characterization experiments of cell therapy starting materials and drug products to answer high priority targeted questions (such as investigation of product mechanisms of action MoA, responses agencys information requests, manufacturing investigations, etc
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