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Research Opportunities - Cardiology
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Full-time
- The Sah laboratory at Washington University School of Medicine in St. Louis (Department of Internal Medicine, Cardiology) and the Center for the Investigation of Membrane Excitability Disease (CIMED) studies the mechanisms of Transient Receptor Potential (TRP) and LRRC8a/ SWELL1 ion channel regulation and signal transduction.
- Broadly speaking, the overarching goal of the Sah laboratory is to understand how ion channels and mechano-signaling influence cellular and organismal metabolism.
- We also combine medicinal chemistry with cryo-EM structure, molecular docking, and functional studies to guide synthesis of novel ion channel modulators for the treatment of human disease.
- Strong background in cell biology and protein biochemistry with an interest in electrophysiology and ion channel biology.
- Working knowledge of computer software (Excel, Photoshop, and Prism) and general lab equipment.
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