Cornerstone Search Group

Build QSP models integrating biological, pharmacological, and physiological data to support drug development at all stages, from preclinical research to clinical trials and beyond, aiding in dose optimization, biomarker identification, safety and efficacy assessment, drug development decision-making, etc.. PhD in a relevant field (e.g., biology, math, pharmacology, biomedical engineering, chemical engineering, computation biology, computer science, etc.). VP, Data Science RWE | Top 5 Pharma. VP, Head of HEOR (Health Economics & Outcomes Research | Top CNS specialty pharma. Head, Patient Advocacy | European commercial-stage rare disease biotech

modeling

QSP Modeling Head (research through clin dev)<ul><li>$5Bn Pharma – Oncology & CNS</li><li>New York City (hybrid)</li><li>Retained Search</li></ul> Cornerstone Search Group has been retained by a profitable and stable European pharmaceutical company which prides itself on a work environment that reflects its country’s renowned culture, has a healthy market cap, is Oncology and Neurology focused, and recently set up in New York City its first US-based R&D hub. This hybrid role is a newly created cross-functional, and wide-ranging Quantitative Systems Pharmacology strategic leadership position. As QSP domain owner, you will lead the efforts of building this new dedicated capability. You will report to a dynamic, and digitally oriented R&D leader who reports to the Global Head of R&D and leads an agile and entrepreneurial department that develops and deploys advanced analytics and innovative methodologies with the aim of unearthing new insights and streamline research processes in order to reshape healthcare outcomes. With a product portfolio featuring a recent blockbuster and the upcoming launch of another anticipated blockbuster, this company is in a very active phase of building out their clinical pipeline through both in-house research and in-licensing efforts. Our client is seeking an entrepreneurial professional who will be excited to build a dedicated QSP capability as part of this company’s shift in R&D philosophy to a more digital and data-driven approach. 5 ATTRACTIVE FEATURES:<ul><li>Uniquely attractive opportunity to lead the efforts of building a dedicated QSP function for a well-financed, public company with a multi-billion-dollar market cap but a small company feel with very few layers.</li><li>Our client’s lead marketed drug is an oncology blockbuster, and their lead clinical candidate is in Phase III and is anticipated to also become a blockbuster. Our client has a long-term focus in Oncology and CNS / Neurology and has a proven history of discovering and developing multiple drugs that have been marketed in the US by multiple Big Pharmas. Our client is now focused on taking the next step in their growth to become a globally integrated pharma.</li><li>This company takes a lot of pride in its culture, reflecting its country’s heritage as having one of the world’s most positive populace.</li><li>You will work closely with the senior leaders in R&D (Discovery through to Pre-clinical and Clinical Development) on integrating QSP modeling into all facets of R&D. You will have the opportunity to develop strategies and processes for a role that will have great strategic impact on the company, which is undergoing an exciting metamorphosis by becoming a more digital, data-driven R&D enterprise.</li><li>In addition, you will share in the responsibility to shape the future of the company’s presence in the US, which was only recently established.</li></ul> LOCATION: New York City (on-site or hybrid)Our client will consider candidates who live outside of New York City (such as NJ, PA, CT, NY State) and in the Northeast/Atlantic states (MA, MD, DC, DE, RI) who prefer/require a hybrid work arrangement where they only work on-site on a limited basis. WORK AUTHORIZATION: Our client will consider candidates who require an H-1B transfer, TN-Visa, or equivalent, as well as Green Card / Permanent Resident sponsorship. COMPENSATION: Highly competitive compensation RESPONSIBILITIES in a NUTSHELL:<ul><li>Build QSP models integrating biological, pharmacological, and physiological data to support drug development at all stages, from preclinical research to clinical trials and beyond, aiding in dose optimization, biomarker identification, safety and efficacy assessment, drug development decision-making, etc.</li><li>Collaborate with internal and external experts, teams, and projects, helping to develop innovative methods for modeling efficacy and safety.</li><li>While part of their computational biology team, you will create your own methods and pipelines, prominently contributing to their shift towards more data-driven research and development.</li><li>Extensive collaboration with internal/external functions, partners, and research biologists is expected.</li></ul> DESIRED SKILLS / QUALIFICATIONS / EXPERIENCES / BEHAVIORS: <ul><li>PhD in a relevant field (e.g., biology, math, pharmacology, biomedical engineering, chemical engineering, computation biology, computer science, etc.)</li><li>Senior / Principal / AD / Director-level QSP experience either with a pharma/biotech or for a consulting company or academic research department that services pharma/biotech.</li><li>Extensive experience with exploratory data analysis, modeling and simulation with programming languages such as Python and R is required.</li><li>Our client is open on therapeutic areas of experience/expertise. Oncology, Neurology, and/or Immunology experiences are a plus.</li><li>Seeking someone who values being part of and contributing to a company that is very culture focused. Seeking excellent team working skills and the communication ability to positively encourage and energize others to reach high performance. Seeking someone who is transparent, flexible, builds trusting relationships, and is highly collaborative.</li><li>Seeking a proactive, self-motivated, and entrepreneurial individual who has the ability to prioritize and get things done.</li><li>Seeking a biotech mindset - someone who is innovative and gets excited when looking into new ideas and acquiring scientific knowledge.</li></ul> CONTACT: Corey S. Ackerman, JD | Senior Partnercackerman@cornerstonesg.com | http://www.linkedin.com/in/coreyackerman973.656.0220 x 716 CORNERSTONE SEARCH GROUP - Life Sciences Executive Search1200 Morris Tpke, Suite 3005 | Short Hills, New Jersey (USA)www.cornerstonesg.com Cornerstone Search Group, recognized by Forbes as one of the "Top 100 Executive Search Firms" and by Hunt Scanlon as one of the "Top 50 Healthcare & Life Sciences Executive Search Firms", is a Life Sciences Executive Search firm that helps companies based around the world, ranging from startup biotechs to Top 10 pharmas, to find, attract, and hire talent for their US and globally based leadership positions (CxO and xVP levels) as well as their critical Director-level roles. Representative Retained Search Assignments:<ul><li>CEO | specialty pharma start-up</li><li>CEO | regenerative medicine start-up</li><li>US CEO | established European small pharma</li><li>President/US Commercial Head | generics pharma</li><li>CMO | late-stage public biotech</li><li>CMO | mid-size pharma</li><li>CSO | mid-size global biotech</li><li>SVP, Head of Global Medical Affairs | mid-size oncology company</li><li>SVP, Head of Global Clinical Development | multi-TA mid-size pharma</li><li>SVP, Head of Global Regulatory Affairs | late-stage Israeli biotech</li><li>Group VP, Global Commercial Head | API Business Unit | Indian pharma</li><li>VP, Data Science RWE | Top 5 Pharma</li><li>VP, Head of Regulatory Affairs | Boston biotech</li><li>VP, US Head of Regulatory Affairs | Top 20 Pharma</li><li>VP, Head of R&D Operations | Boston biotech</li><li>VP, Head of HEOR (Health Economics & Outcomes Research | Top CNS specialty pharma</li><li>VP, Head of US HEOR & RWE | Top 5 Pharma</li><li>VP, Head of Real-World Evidence | Top 5 pharma</li><li>VP, Head of US HEOR | Top Oncology Pharma</li><li>ED, Head of HEOR | Top West Coast Pharma</li><li>VP, Head of Global Market Access | Top Oncology Specialty Pharma</li><li>VP, Head of US Market Access | High-profile late stage biotech</li><li>VP, Head of US Market Access | West Coast Late-Stage Public Biotech</li><li>VP, Head of Heme/Onc Clinical Research | Public oncology biotech</li><li>VP, Head of Clinical Development | late-stage anti-infectives UK pharma</li><li>VP, Head of Global Drug Safety & PV | Chinese oncology biotech</li><li>ED, Head of Clinical Operations | British VC-backed biotech</li><li>ED, Global Commercial Strategy Franchise Head | Top rare disease Boston pharma</li><li>ED, Head of Global Clinical Pharmacology | Public oncology biotech</li><li>ED, Head of Global HEOR | Large US Pharma</li><li>Head, Patient Advocacy | European commercial-stage rare disease biotech</li><li>Medical Directors (Director/SD/ED levels) in Translational Medicine / Clinical Development / Medical Affairs / Drug Safety: 75+ retained assignments</li><li>HEOR/RWE/Market Access (AD/Director/SD/ED levels): 100+ retained assignments</li></ul> Cornerstone’s Privacy Policy: Cornerstone Search Group considers all inquiries, resume submissions, and any other personal information submitted to us as confidential information. This information will not be shared with any parties outside of Cornerstone Search Group without your prior permission. CaQSPorfin3156 Keywords: cancer pain Alzheimer’s Parkinson’s multiple sclerosis AD associate director

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