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Postdoctoral Research Associate
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$35
- Attention immunologists and/or genetics/genomics experts: the Ray Lab and Harrison Lab at the Benaroya Research Institute have a joint post-doctoral fellow position open to conduct research on a funded project pertaining to genetic risk for inflammatory bowel disease and how genetic mutations influence T cell function during intestinal inflammation.
- Together, our collaborative efforts seek to define how human genetic variation contributes to disease through performing CRISPR genome editing and other functional genomic approaches in immune cells and define how genetic risk alters cellular expression and function in human cells and mouse models of IBD. Dr. Ray has affiliate appointments at the University of Washington Departments of Immunology and Genome Sciences.
- Immunologist and/or genetics/genomics expert: will analyze genetic variants and their effects on enhancer and promoter function in immune cells in vitro, through performing massively parallel reporter assays and high-throughput CRISPR screens in human primary T cells from IBD patients and healthy controls.
- Mapping enhancers that control T cell function and their target genes at steady state and in infection and autoimmunity using bulk and single cell CRISPR screens.
- In vivo enhancer screening in autoimmune mouse models.
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