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Associate Director, RNA Purification & Characterization
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- Expertise is required with how RNA secondary structure and topology affects both its generation (in vitro or in vivo) and its function.
- Your primary role involves management and hands-on research including purification process development and analytical development / characterization of mRNA and circRNA, with the ultimate aim of producing therapeutic-grade material for in-vitro downstream assays and deliver scalable purification strategies to reduce immunogenicity and maximize in-vivo expression.
- Lead a small team in circRNA / mRNA purifications, analytical method development and develop novel scalable processes to deliver therapeutic-grade material for in-vitro and in-vivo studies.
- Develop scale-out and scale-up mRNA and circRNA processes using liquid handling systems (Hamiltons, HPLCs, FPLC and others) to deliver high purity mRNA / circRNA including chromatography based purification, analytical methods and IVT reactions.
- PhD with a minimum of 5 years of experience or equivalent experience in Biochemistry, Chemical Engineering, Molecular Biology, Biological Sciences, Chemistry, or a related field.
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