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Upstream processes include tissue culture, cell bioreactors, fermentation, virus propagation, cell and virus bank production, and buffer/media preparation. Our innovative culture will allow interested candidates to discover and create, through collaboration, cutting edge solutions to tough problems.
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Bachelor’s or Master’s degree from an accredited institution with a relevant scientific discipline such as Chemistry, Biology, Biochemistry, Molecular Biology, Protein Chemistry etc. Downstream unit operations include harvest, clarification, chromatography, centrifugation, TFF (UF/DF), filtration, formulation, and fill-finish.
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We seek a technically skilled, self-motivated, and meticulously organized stem cell scientist with expertise in primary cell culture, including embryonic stem cells (ESCs) and/or induced pluripotent stem cells (iPSCs.
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Technical requirements for this position include first-hand experience in the analysis of large-scale biological data, proficiency in cell and tissue culture, molecular biology skills, and an interest in working with transgenic animals and disease models.
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We will use multidisciplinary approaches including cell culture and both acute (AAV-injected) and chronic mouse models of Alzheimer’s disease Candidate will be responsible for performing all the experiments proposed for this project, including mouse learning memory behaviors, Western blot analysis and qRT-PCR, quantitative histology and RNAseq analysis.
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Candidates should have experience with the techniques of protein biochemistry, cell culture, microscopy, and animal experiments. Memphis boats attractions, including Elvis Presley's Graceland, the Memphis Grizzlies, historic Beale Street, the National Civil Rights Museum, the second-largest urban county park in the United States, and the Memphis in May World Championship Barbecue Cooking Contest.
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Genome engineering, high-throughput genomics, next-generation sequencing, protein engineering, structural biology, liquid handling automation, hematopoietic stem cell cell culture and transfection, and data science.
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Participate in all aspects of manufacturing activities including raw material support, cell culture, and continuous improvement. QUALIFICATIONS:-AS or BS in a scientific field strongly preferred-Must be able to work in a clean room environment that potentially includes hazardous materials, and Medical equipment (including blood, tissues, and needles)-Must have ability to perform algebraic math-Must be detail oriented and have excellent organizational skills-Must possess effective written and oral communication skills-Must display a high degree of professionalism and confidentiality.
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We will use multidisciplinary approaches including cell culture and both acute (AAV-injected) and chronic mouse models of Alzheimer’s disease. We are seeking a postdoctoral trainee for studying cellular, ion channel and synaptic circuitry mechanisms in Alzheimer's disease cell and mouse models.
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Offering a variety of services such as contamination and impurity testing, protein characterization, bioassays, viral clearance studies and stability and lot release programs, we support clients throughout the biologic development cycle, from the establishment and characterization of cell banks through preclinical and clinical studies to marketed products.
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The ideal candidate will also have experience in basic bench laboratory techniques such as (but not limited to) real-time PCR, SDS-PAGE, and sterile cell culture. Perform basic laboratory tasks such as experimental sample preparations, centrifugation, pipetting, cell culture, preparing tissue samples, and other routine laboratory techniques.
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This individual will assist researchers with laboratory experiments by preparing reagents and samples, performing basic cell culture and other basic laboratory techniques, setting up equipment, and troubleshooting experimental procedures or equipment function.
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