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Preferred: Proficiency in knowledge of raw materials including cell culture media, chemicals, and excipients used in biotherapeutic products. The Material Sciences department at Janssen TDS-Biologics is seeking a candidate to support cell and gene therapy (CGT) development, including CAR-T therapies, related to raw materials for our growing advanced therapies' portfolio.
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Under supervision and guidance, the Process Technician of Upstream Operations will be responsible for hand-on executing the routine operation, maintenance, and periodically requalification of cell culture based upstream production equipment and production suites in a cGMP biopharmaceutical pilot plant.
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Detail oriented, excellent organization skills and communication skillsBasic skillsets required: mammalian cell culture, ELISA, Flow Cytometry, DNA/RNA extraction, and PCR is major plus for this role.
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Under the direct supervision and guidance of senior staff, the Upstream Operations Process Technician will play a hands-on role in the routine operation, maintenance, and periodic requalification of cell culture-based upstream production equipment and production suites in a cGMP biopharmaceutical pilot plant.
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Experience in aseptic processing and mammalian cell culture production. The ideal candidate will possess a robust technical proficiency encompassing PCR, flow cytometry, cell culturing, and ELISA methodologies.
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The Upstream Manufacturing Specialist of Upstream Operations will be responsible for hand-on executing the routine operation, maintenance, and periodically requalification of cell culture based upstream production equipment and production suites in a cGMP biopharmaceutical pilot plant.
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In addition, the individual will execute and participate in the execution activities for scale-up and system operations supporting the manufacture of preclinical, clinical, and commercial biologics drug substances, including operation of cell culture bioreactors and harvest equipment, GMP documentation, and ensuring compliance to relevant regulations.
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PhD in Biological Science, Biochemical Engineering, or related discipline with 0-2+ year's relevant industrial analytical development experience, or MS with 0-4+ year's analytical development experience for biologics.
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Company Summary At Saint-Gobain, our employees have pride in belonging to an organization whose culture is made up of these core values: Trust, Empowerment, & Collaboration. Company Summary At Saint-Gobain, our employees have pride in belonging to an organization whose culture is made up of these core values: Trust, Empowerment, & Collaboration.
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Excellent aseptic skills and broad cell culture bioreactor and biochemistry analytical knowledge and experience. Minimum of 8 years (BS) or 5 years (MS) practical scientific experience preferably in the mammalian cell culture and harvest process.
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Support cell culture and protein purification as needed. Mammalian cell culture experience. Prior experience with cell-based cytotoxicity and internalization assay, protein expression, and purification on AKTA instruments is a plus.
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Prior industry/academic experience with cell culture, protein expression, and purification on AKTA or other chromatography instruments is a requirement. Our proprietary memory B cell hybridoma technology allows for the rapid screening and functional characterization of novel antibodies and targets.
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At Saint-Gobain, our employees have pride in belonging to an organization whose culture is made up of these core values: Trust, Empowerment, & Collaboration. Liaison with customers as requested in alignment with CertainTeed Corporation and Saint-Gobain Principles of Conduct and Actions.
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Saint-Gobain is an equal opportunity employer of individuals with disabilities and supports the hiring of veterans. Saint-Gobain provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, gender, sexual orientation, gender identity or expression, national origin, age, disability, genetic information, marital status, amnesty, or status as a covered veteran in accordance with applicable federal, state and local laws.
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cell culture biological jobs in Exton, PA
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