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Build QSP models integrating biological, pharmacological, and physiological data to support drug development at all stages, from preclinical research to clinical trials and beyond, aiding in dose optimization, biomarker identification, safety and efficacy assessment, drug development decision-making, etc.
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Provide in vitro biology and pharmacology support and collaborate with other drug discovery functions to advance preclinical programs and achieve company milestones. Collaborate closely with chemistry and ADME pharmacology teams in closed-loop lead optimization campaigns.
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Position Summary: The Senior Technician in the Discovery Technologies In vivo pharmacology group will be part of a dynamic group of scientists conducting various research projects to identify large molecule/biologics which can effectively treat various forms of cancer.
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Ph. D. or equivalent in a relevant scientific discipline (e.g., biochemistry, molecular biology, pharmacology) Collaborate closely with colleagues in other functional areas, including chemistry, pharmacology, and clinical development, to integrate biology insights into overall drug discovery and development efforts.
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O Ph. D. in immunology, oncology, pharmacology, cell biology or related field, o Technical and strategic leadership spanning preclinical discovery and translational research, with a focus on.
Full-timeExpandApply NowActive JobUpdated 2 months ago - UpvoteDownvoteShare Job
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Experience in preclinical in vivo imaging such as PET, MRI, CT or SPECT. We are searching for a Senior Scientist to lead preclinical discovery research services. PhD or MSc (with equivalent experience) in a relevant field (e.g., Biology, Biochemistry, Pharmacology, Physics, Engineering.
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They will interact daily with our data science and computational group for interpretation and design, our biology and pharmacology group to develop assay workflows for in vivo translation, and our chemistry group to push the boundaries of what is possible with parallel chemistry and library syntheses.
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Interface broadly with key functions including discovery sciences, preclinical development groups, toxicology, clinical operations, drug metabolism, regulatory affairs, and late-stage clinical research.
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Cancer pharmacology, translational research, drug discovery, drug development. Ph. D. in pharmacology, oncology, cell biology, or a related discipline, with 2-5 years of post-doctoral and at least 8-10 years of relevant industry experience in cancer drug discovery and development.
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Implementation of PK-guided dose escalation, early combination strategies and emerging innovations on all Pfizer Oncology first-in-human clinical trials with input from Oncology Research Unit, Oncology Regulatory Strategy, Clinical Pharmacology and Precision Medicine, Oncology Clinical Development and Operations, Pharm Sci and Product Teams.
$253,800 - $410,600 a yearFull-timeExpandApply NowActive JobUpdated 3 days ago - UpvoteDownvoteShare Job
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Twelve of the programs we've worked on with collaborators have progressed into preclinical development, with nine currently in clinical trials. In so doing, you'll maximize efficiencies through positive relationships with internal stakeholders (e.g., translational research, data management, clinical operations, clinical research, and clinical pharmacology) as well as external stakeholders (e.g., clinical sites and CROs.
$150,000 - $200,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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The In vivo Pharmacology Senior Scientist/Principal Scientist will execute experiments, and will also be responsible for performing or collaborating in vivo PK/PD studies done in preclinical models including ex vivo assays (i.e. ELISA based PD read outs.
Full-timeExpandApply NowActive JobUpdated 10 days ago
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