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What You Will Need:Graduate degreeMinimum 4 years of relevant experienceGood understanding of genomics, molecular biology, and technologies such as qPCR and next-generation sequencing. This opportunity is a full-time position with Guidehouse, and it is on-site in Rockville, MD.What You Will Do:Implement, design, develop, and innovate current and emerging computational biology and bioinformatics algorithms to analyze, manage, interpret, visualize, and illustrate original scientific data.
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Basic knowledge and experience in DNA extraction and DNA sequencing library preparations. Assist in the instruction and execution of Next-Generation Sequencing teaching courses offered by the MRSN that involve whole genome sequencing assembly and analysis using a variety of software tools to better understand bacterial epidemiology and antibiotic resistance.
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The Laboratory of Integrative Multiomics, led by Dr. Rasmi Thomas, uses cutting-edge next-generation sequencing technologies to identify factors involved in host-pathogen interactions. Masters Degree required, PhD in Bioinformatics or Computational Biology preferred.
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We are seeking a highly motivated, independent scientist to join our Development, Optimization & Implementation team to establish and support new pipelines for extraction and downstream technologies required to support DCEG investigators in areas of human, bacterial, and viral nucleic acid research applications including metagenomics, targeted sequencing applications, and ctDNA and cfRNA sequencing.
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In molecular biology techniques such as cloning, site-directed mutagenesis, DNA and RNA isolation and purification, sequencing, RT-PCR, and qPCR. of DNA sequencing techniques (NGS and Sanger) and sequence analysis.
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TASKS. The contractor shall: Perform a wide range of complex procedures and techniques including cell culture, molecular biology, DNA/RNA analysis, DNA/RNA isolation, DNA/RNA purification, DNA/RNA next generation (Illumina) sequencing, flow cytometry, and gene cloning.
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Perform, with technical independence, basic and advanced laboratory procedures such as in vitro cell culture of the malaria parasites, PCR, qPCR, bacterial identification with mass spectroscopy, detection of P. falciparum biomarkers from RNsequencing data and whole genome sequencing analysis.
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Strong background in Computer Science, Statistics, Genomics, Genetics, RDBMS, Cloud Computing, Google APIs, Bioinformatics and Computational Biology required. In addition, designs, develops, and guides the implementation of software solutions that aid in the visualization and analysis of Next-generation Sequencing data (NGS.
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Use advanced knowledge in machine learning, statistics, text mining, natural language processing, computational semantics, computer vision, and data science to develop creative solutions to complex real-world problems.
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Knowledge and experience in DNA extraction and DNA sequencing library preparations. + Provide support to the implementation of a high-throughput whole genome sequencing of the MRSN isolate collection and produce from 1,000 to >2,000 high-quality (i.e., in conformity with detailed summaries and with clear QC thresholds) draft bacterial genome assemblies monthly.
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Molecular Laboratory (CLIA and CAP accredited) performing Next Generation Sequencing. American Board of Medical Genetics and Genomics (ABMGG) certification in Clinical. Molecular Laboratory (CLIA and CAP accredited) performing Next Generation Sequencing.
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Maintain accurate, daily records of experiments and results in pen in bound laboratory notebooks and perform procedures such as molecular techniques, RNA/DNA extraction, RT-PCR, Real Time PCR, immunostaining, flow cytometry, maintaining cell cultures, ELISAs, Western blot, preparation and analysis of RNA/DNA sequencing, in vivo inoculations, necropsy, and tissue collection/processing; experimental design, and basic statistical analysis.
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Our research entails the functional annotation of somatic mutations in candidate driver genes previously identified by next generation sequencing of endometrial tumor tissues. Access to extensive core facilities including cores in bioinformatics, microarrays, copy number analysis, flow cytometry, cytogenetics, and a transgenic mouse core, offers the trainee wide latitude in the design and pursuit of their research questions.
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Protocols will include microbial growth, flow cytometry, DNA extraction, and sequencing library preparation. PREP is a 5-year cooperative agreement between NIST laboratories and participating PREP Universities to establish a collaborative research relationship between NIST and U.S. institutions of higher education in the following disciplines including (but may not be limited to) biochemistry, biological sciences, chemistry, computer science, engineering, electronics, materials science, mathematics, nanoscale science, neutron science, physical science, physics, and statistics.
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Conduct computational structural studies of proteins complexes, macromolecular assemblies, and cellular processes by using processed light and electron microscopy data. Maintain and support staff for conducting computational analysis via molecular modeling, docking and molecular dynamics to gain insights into biomolecular mechanisms and structure-activity relationships.
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computational sequencing jobs in Rockville, MD
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