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PhD in immunology, cancer biology, cell biology, toxicology, pharmacology, or related field with experience preferably in industry or academic setting. As a Senior Scientist, you will design and implement experimental strategies to improve our investigative toxicology capabilities and drive our safety science forward to advise the design and selection of drug candidates with the “right safety” profile.
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Lead early stage pipeline programs, including process development, scale-up, toxicology material production, technology transfer, clinical material manufacturing support, analytics, formulations and IND submissions, to support development of molecules leading to commercialization.
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PhD in immunology, cancer biology, cell biology, toxicology, pharmacology, or related field with experience preferably in industry or academic setting with a minimum of 3 years' experience. As an integral member of our multi-disciplinary drug discovery teams, you will direct investigative toxicology strategies to predict, assess and mitigate target- and modality-related safety risks in discovery programs.
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Toxicologist, Developmental and Reproductive Toxicology. M.S. or Ph. D. in toxicology or related field and at least 2 year experience preferred. Toxicologist, Developmental and Reproductive Toxicology.
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We rely on you to build effective cross-functional networks across CPSS and Early CVRM and with a curious mind seek opportunities for collaboration on safety and efficacy (e.g. animal model development, multimodal and in vivo imaging, mechanistic toxicology and disease pathophysiology.
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Plan, design, and execute IND-enabling pharmacology, pharmacokinetic and toxicology studies by applying knowledge of disease-associated pathways, preclinical models, and drug development. cancer biology, immunology, molecular biology, bioinformatics) with 0-2 years’ experience in drug discovery or drug development.
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Masters in immunology, cancer biology, cell biology, toxicology, pharmacology, or related field with 5+ years experience preferably in industry or academic setting. You will also maintain technical expertise in preclinical safety approaches applied to Immuno-Oncology therapeutics or Antibody Drug Candidates and awareness of industry trends.
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PhD, MD or MD/PhD degree in a relevant scientific field (e.g., cancer biology, immunology, molecular biology, bioinformatics) with 0-2 years experience in drug discovery or drug development. The TSS will be an integral member of cross-functional project teams and will be accountable for developing and driving implementation of translational plans, identifying preclinical models with mechanistic alignment to human disease, defining the preclinical and early clinical biomarker strategy, and helping to build the early clinical development plan.
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DPI has both technology development components and collaborative resource access programs, covering small molecule and RNAi screening technologies and informatics, and catalyzes translational efforts in biology, medicinal chemistry, pharmacokinetics, toxicology, absorption, distribution, metabolism, excretion (ADME), and project management.
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Expert knowledge in drug development principles (pre-clinical and clinical toxicology, translational medicine, clinical biomarkers, etc.) Expert technical knowledge as it relates to phase gated assay development, pre-clinical and clinical sample testing and bioanalysis (GLP/GCLP/GXP.
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Serves the primary clinical voice for the project at governing bodies such as Development Review Board (DRB) Research Review Board (RRB) and technical committees such as Global Safety Board (GSB), Protocol Review Board (PRB) and Toxicology Working Group (TWG.
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Maintains up to date training in GLP in support of toxicology studies and GCLP in support of clinical trials. The Scientist will also support assay development, optimization and validation, utilizing immunohistochemical (IHC) and in situ hybridization (ISH) techniques.
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The Scientist position is a hands-on laboratory position responsible for performing all tasks associated with histology including but not limited to routine and non-routine sample processing, embedding, microtomy, staining, and sample management.
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Performs routine and non-routine histology including but not limited to histology, grossing, processing, embedding, microtomy, and staining. The Scientist will also perform assay interpretation and documentation, and will work closely with pathologists and team members to provide the highest quality assay performance in support of experimental research and clinical (GCP) projects.
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Works in compliance with Good Laboratory Practices (GLP) and Good Clinical Laboratory Practices (GCLP) regulations. Performs routine and non-routine automated immunohistochemistry. Experience using automated IHC staining platforms preferred.
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toxicology job in Gaithersburg, MD
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