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BS/MS degree in Protein Biochemistry, Molecular Biology, or similar. Protein biochemistry and molecular biology experience. Help troubleshoot and optimize protein engineering, expression, purification, and formulation processes.
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Experience with tissue culture, western blots, or protein purification. Degree or coursework in biology, biochemistry, genetics, cellular biology, bioengineering or bioinformatics.
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Conduct research on projects associated with antimicrobial development such as protein expression and purification, MIC (minimum inhibitory concentration) studies, animal modeling, virtual modeling of drugs bound to target proteins, etc.
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PhD in Biochemistry, Chemistry, Chemical Engineering, Pharmaceutical Sciences, life sciences or equivalent amount of experience and a minimum of 15 years of biotech industrial experience working with cell culture, purification, analytical, and/or formulation development.
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You'll be instrumental in guiding research, development, and the application of cutting-edge methodologies in areas of genomics, protein chemistry, physical biochemistry, and drug discovery, with a particular emphasis on oncology and immunology.
$92,000 - $145,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Perform immunoassays, flow cytometry analysis, mammalian and bacterial cell cultures, DNA preparation, and protein purification. The research is highly interdisciplinary, relying on tools from molecular biology, biochemistry, structural biology, AI-based structure prediction, transgenic models, immunology, and neuroscience, but also including industrial collaboration.
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Researchers in this group express, purify and crystallize ESKAPEE pathogen proteins of interest and utilize sophisticated techniques such as X-ray Crystallography and Mass Spectroscopy to model small molecule drug-protein interactions.
$85,000 a yearFull-timeExpandApply NowActive JobUpdated 20 days ago - UpvoteDownvoteShare Job
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Perform biochemical assays, protein expression and purification, assess sample quality, prepare samples for analytical studies included but no limited to spectroscopy (absorption, fluorescence, circular dichroism), determine binding constants by various methods (spectroscopic, analytical centrifugation, size-exclusion chromatography, SEC-MALS, DLS and related.
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Protein purification using immunoaffinity purification. Measurement of molecules in vitro: Electrophoretic mobility shift assay (EMSA) for protein-DNA or protein-RNA interactions, Co-immunoprecipitation to detect protein-protein or protein-RNA interactions.
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The Manufacturing Associate I/II participates in the manufacturing of biopharmaceutical drug product to support MacroGenics' multiple clinical programs in the Protein Purification area. Knowledge of protein purification techniques.
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Good understanding of techniques used in protein development, screening & testing; protein purification, and analysis (western blot, ELISA, IHC, ICC, IF, Flow, IP, affinity purification, ion-exchange chromatography, FPLC, SDS-PAGE) and its applications; Lab experience in these areas is preferred.
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Experience with microbiology of Gram-negative species, antibacterial development, genetics and molecular cloning to determine and develop target antigens, eukaryotic cell culture, expression vector design, transient transfection, recombinant antibody testing and development, protein expression.
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A working knowledge of protein biochemistry and characterization would be beneficial. Working knowledge of methods and immunoassay technologies used for large molecules (biologics) analysis, such as ELISA (direct and indirect sandwich formats), Luminescence, Colorimetric, Electrochemiluminescence (MSD), etc.
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Perform molecular biology/virology methods including but not limited to DNA extraction and purification, PCR, RT-qPCR, molecular cloning, gel electrophoresis, transfections, bacterial transformations, recombinant protein production/purification and microscopy.
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PhD or Master's degree preferred; background specifically in proteomics (protein purification and antibody development) PhD or Master's degree preferred; background specifically in proteomics (protein purification and antibody development.
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biochemistry protein purification jobs in Bethesda, MD
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