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Responsibilities Support the development of the Drug Substance strategy and oversee manufacturing of preclinical and clinical material. Senior Director, Drug Substance Position Summary Reporting to the VP, Head of CMC Development, the Senior Director, Drug Substance will be responsible for leading the drug substance team in development and manufacturing as part of PepGen ́s CMC team.
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Strong subject matter expertise in immune-oncology, cell therapy drug discovery and development including CMC considerations, CAR design, engineering and armoring strategies, innate immune cells such as NK and gamma delta for the purposes of leading drug development projects from start to the clinic.
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As part of the Discovery Biotherapeutics efforts at BMS, the Principal Scientist will play a key role in advancing antibody drug conjugates technologies at BMS. The Discovery Biotherapeutics team at BMS seeks to understand the structure and function of complex molecules such as bispecific antibodies, antibody drug conjugates and endogenous proteins in order to optimize their utility as therapeutic agents.
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Qualified candidates must have a PhD in synthetic/organic chemistry or related scientific field with 15+ years’ experience in drug substance development and manufacturing and a proven track record in developing and scaling up chemical process to kilo lab, pilot plant and commercial plant scales.
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The Infusion Pharmacist II is responsible for the optimization of drug therapy by identifying, resolving, and preventing drug-related problems and adverse drug events. Ability to utilize references and/or drug information sources.
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Analytical Skill, Analytical Skill, Analytical Thinking, Chemical Biology, Chemistry, Clinical Trials, Communication, Curiosity, Data, Data Analysis, Design of Experiments (DOE), Detail-Oriented, Drug Development, Drug Discovery Process, Ethics, Gene Therapy, Group Problem Solving, Immunology, Inventory Management, Laboratory, Large Group Presentations, Leading Project Teams, Life Science, Machine Learning (Ml), Medical Research {+ 9 more.
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PREFERRED : M.S.; relevant experience with micromolding techniques, nanoparticle synthesis, and/or microneedle fabrication; experience with characterizing drug delivery materials, biological assays, controlled release, biomaterials, chemistry, protein stability, molecular biology, immunology, and/or virology; and experience working with animals.
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Delphia is searching for an Associate Director / Director, Drug Metabolism and Pharmacokinetics to join the team! Work collaboratively with the toxicology team and future translational pharmacology and clinical development teams to support the progression of therapies from late discovery through first in human clinical studies integrating DMPK data into the overall drug development strategy.
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This team is searching for a Principal Scientist, ADME. You will be collaborating with the Preclinical and Analytical Sciences group, to manage ADME lab operations and support small molecule drug discovery programs for cardiovascular indications.
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Experience advising on statutes, regulations, and guidance documents applicable to market access activities, including Medicaid, 340B program, Veterans Administration, federal and state anti-kickback statutes, state drug pricing transparency laws, OIG guidance documents and advisory opinions, the False Claims Act, and the PhRMA Code.
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Experience in protein/protein, protein/RNA, RNA/small molecule or protein/small molecule interactions by DSF, ITC, and/or MST and have applied these to small molecule drug discovery preferred. You will be the Biochemistry lead on projects and play a key role in drug discovery.
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Collaborate with quality and regulatory teams to ensure drug material meets cGMP standards. This person is primarily responsible for ensuring that timelines are achieved to ensure drug supply for clinical trials.
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Alloy’s Translational Research team supports our drug discovery partners with in vitro and in vivo testing of therapeutic drug candidates across multiple modalities. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma.
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Collaboration: Collaborate closely with cross-functional teams, including bioinformatics, medicinal chemistry, biology, and machine learning, to integrate computational biology approaches into drug discovery projects.
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Ideally, you will have experience using multiple assay formats in the context of drug discovery/therapeutics. We couple novel technologies and approaches to industry-standard drug discovery rigor to tackle some of the most challenging targets across a wide range of disease areas, specifically for this position, autoimmunity and IBD.
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drug screen jobs Title: associate in Woburn, MA
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