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As part of the Discovery Biotherapeutics efforts at BMS, the Principal Scientist will play a key role in advancing antibody drug conjugates technologies at BMS. The candidate is expected to have strong collaborative skills to ensure robust partnerships with biologists, antibody discovery and engineering & bioanalytical scientists to advance ADC projects.
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We have developed a drug-discovery platform that integrates computational chemistry, structural biology, chemical biology, target-informed screening, and mechanism-driven pharmacology to develop small-molecule therapeutics that specifically modulate ferroptosis.
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This is a unique opportunity for a PhD-level biologist to be involved in high-impact drug discovery projects in the newly developed Center for Therapeutic Discovery at Dana-Farber Cancer Institute.
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Analytical Skill, Analytical Skill, Analytical Thinking, Chemical Biology, Chemistry, Clinical Trials, Communication, Curiosity, Data, Data Analysis, Design of Experiments (DOE), Detail-Oriented, Drug Development, Drug Discovery Process, Ethics, Gene Therapy, Group Problem Solving, Immunology, Inventory Management, Laboratory, Large Group Presentations, Leading Project Teams, Life Science, Machine Learning (Ml), Medical Research {+ 9 more.
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Provide scientific direction and pathology expertise to project specific IHC, ISH and spatial endpoints in collaboration with the DSRE Investigative Pathology and Toxicology labs, DMPK, and Drug Discovery Unit translational pathology groups.
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Possessing in-depth knowledge of antibody-based discovery, optimization/ engineering using in vivo based discovery methods that include transgenic animals/ llamas and single B cell cloning methodologies and NGS to manipulate and mine antibody populations appropriately for therapeutic antibody workflows.
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The Research Associate I, Downstream CMC (Contract) position will support the Company’s intracellular biologics discovery programs. They will work closely with downstream and upstream teams to progress discovery and development programs.
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Collaborate with the Project Management and CMC teams and related functions, including discovery, non-clinical development, Formulation, Analytical Development, QA, and CMC Regulatory Affairs. Qualified candidates must have a PhD in synthetic/organic chemistry or related scientific field with 15+ years’ experience in drug substance development and manufacturing and a proven track record in developing and scaling up chemical process to kilo lab, pilot plant and commercial plant scales.
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We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development.
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The Hematology group in the Internal Medicine Research Unit (IMRU) is seeking a highly motivated BA/BS scientist with in vivo pharmacology experience to support preclinical drug discovery efforts for Hematology programs.
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As a Scientist II/Sr. Scientist I at NextRNA Therapeutics, you will join an interdisciplinary team of highly creative and talented individuals whose vision is to improve patients’ lives by expanding the space of small molecules targeting RNA. You will have an opportunity to work with a diverse team of biologists, biochemists, chemists, and computational biologists to support drug discovery programs for the next wave of RNA therapeutics.
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By integrating our propriety screening technology using the body’s natural regulators, with our powerful AI-enabled drug discovery platform, we are able to efficiently identify novel, biologically relevant allosteric sites for protein or RNA targets, and rapidly advance structural insights into small molecule therapeutics design.
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Experience in neuromuscular and/or CNS drug discovery preferred. We are seeking an Senior Scientist, Discovery who will report to our Senior Director, Discovery Biology. They will be responsible for executing biochemical and cellular assays to support drug discovery efforts.
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The RoleAs a Lab Technician, Bioanalytical, you will work with our Antibody Discovery Services team to support the discovery of antibody-based therapeutics. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma.
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Alloy’s Translational Research team supports our drug discovery partners with in vitro and in vivo testing of therapeutic drug candidates across multiple modalities. The Translational Research team supports external partners with functional testing of discovery output while also working closely with other scientific teams within Alloy to validate platform innovations and novel technologies.
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discovery job Title: doctoral fellow in Watertown, MA
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