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Proven track record of leading successful in vitro pharmacology efforts in the field of Cell Therapy, including assay development and validation, candidate screening, and mechanism of action studies.
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Transient cell culture techniques such as transfection, cell number and viability monitoring, cell lysis and protein harvest Purification of proteins using liquid chromatography techniques.
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Thymmune Therapeutics is a preclinical biotechnology company based in Cambridge, MA applying proprietary insights in thymic engineering to develop and commercialize iPSC derived immune cell therapy products addressing significant opportunities with unmet clinical need across immunology.
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The patients have a general diagnosis of leukemia, lymphoma, multiple myeloma, sickle cell disease, solid tumor cancers, immune disorders, palliative care, and other hematologic malignancies. The unit provides care for allogenic bone marrow transplants (including CAR-T therapy, umbilical cord blood transplant, matched unrelated donors and Haplo donors) and autologous peripheral blood stem cell transplant patients.
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Comprised of Tufts Medical Center, Lowell General Hospital, MelroseWakefield Hospital, Lawrence Memorial Hospital of Medford, Care at Home - an expansive home care network, and large integrated physician network.
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Demonstrated experience in diverse molecular and biochemical laboratory techniques applied to cell characterization at molecular or genetic levels (immunofluorescence, flow cytometry, qPCR, RNA sequencing)Well organized, self-motivated, team oriented, ability to multitask with attention to detailExcellent communication and writing skillsProficient in computational analysis and coding pipelines (R Studio, Python, etc.
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Proven experience working with complex matrices and cell isolation, ideally also exposure to technologies required for cell and gene therapy products such as NGS, PCR variations including ddPCR, flow cytometry.
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Experience with cell culture, flow cytometry, ELISA/MSD, IHC, qPCR/PCR/ddPCR. Here at Kelonia Therapeutics, we aren't just a preclinical company; we're trailblazers in viral engineering, pushing the boundaries of in vivo lentiviral gene and cell therapy.
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Experience with cell and gene therapy test methodologies (i.e. PCR, Flow Cytometry, ELISA, cell culture, cell-based assays). The ElevateBio ecosystem combines multiple R&D technology platforms – including Life Edit, a next-generation, full-spectrum gene editing platform; comprehensive cell engineering technologies; and an expanded viral and non-viral therapeutic delivery platform – with BaseCamp, its end-to-end genetic medicine cGMP manufacturing and process development business, to accelerate the discovery and development of advanced therapeutics.
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Strong understanding of the Pharma and Biotech industry challenges is needed and ability to develop high level of applications knowledge based on industry and familiarity with most common Sequencing, Synthetic Biology, cell and gene therapies, and molecular biology lab techniques.
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Experience with techniques related to T cell immunology and tumor immunotherapy, such as T cell dependent cellular cytotoxicity assays, cytokine analysis, and flow cytometry (including FlowJo data analysis.
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The ideal candidate will have neuroscience research experience employing a variety of in vitro/in vivo electrophysiology techniques including traditional whole-cell patch-clamp, extracellular field potential recordings, and qEEG. Additional computational or programming experience is also required.
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The Research Nurse in collaboration with the physician, is responsible for the implementation and evaluation of clinical research in their specific program/area.
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Biopharma CGT (Cell and Gene Therapies) is seeking a Senior Manager of Materials Operations to lead a team responsible for multiple GMP warehouses within Vertex's internal Cell and Gene Therapy manufacturing network.
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In addition to basic methods of cell and molecular biology including signal transduction pathways, microRNA and long noncoding RNA, transgenics and gene knock out the Chen Lab has used a number of rodent animal models, in which stem cells, growth factors and advanced matrix scaffolds are applied.
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cell phone jobs Title: sales representative Company: Georgos Wine in Waltham, MA
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