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Proficient at ex vivo tissue processing and downstream analyses using immunostaining, flow cytometry, ELISA and ddPCR. Under the supervision of a senior scientist, this candidate will support study execution for internal in in vivo studies, including rodent models such as rats and mice.
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Demonstrated experience in diverse molecular and biochemical laboratory techniques applied to cell characterization at molecular or genetic levels (immunofluorescence, flow cytometry, qPCR, RNA sequencing)Well organized, self-motivated, team oriented, ability to multitask with attention to detailExcellent communication and writing skillsProficient in computational analysis and coding pipelines (R Studio, Python, etc.
$101,500 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Here at Kelonia Therapeutics, we aren’t just a preclinical company; we’re trailblazers in viral engineering, pushing the boundaries of in vivo lentiviral gene and cell therapy. Familiarity with analytical techniques used for viral vector characterization, such as qPCR, ELISA, flow cytometry, and particle sizing.
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Extensive hands-on experience with standard immunological techniques including multi-parameter flow cytometry, cell sorting, immunoassays such as ELISA, Cytotoxicity, in vitro co-culture assays (MLR, PBMC cultures, etc), and reporter bioassay development.
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Collaborate with Protein Sciences to optimize the developability profiles of candidate molecules, and with In Vivo Pharmacology team to evaluate PK/PD, efficacy, and toxicity. Familiarity with IND-enabling studies and preparing materials for the pharmacology section of an IND.Excellent skills with cell culture such as primary cell culture, stable and transient protein expression, fixed and live cell imaging by IHC or immunofluorescence, flow cytometry.
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Expertise in primary human cell culture, multi-color flow cytometry, multiplex cytokine detection, functional immune cell assays (proliferation, cytotoxicity, chemotaxis) and assay development is essential.
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Expertise in at least one of the following assay methods ELISA, Western blot, qPCR, flow cytometry, ChIP. Implement target-specific assays to assess target and drug activity in vitro and/or in vivo, as appropriate.
$170,500 a yearFull-timeExpandApply NowActive JobUpdated 12 days ago - UpvoteDownvoteShare Job
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Process the collected study tissue and execute molecular techniques for assessing nucleic acids/proteins including but not limited to PCR, ELISA, Western Blots, and Flow cytometry. Are you a skilled RNA analytical scientist with a passion for cutting-edge technology and the drive to make a difference in the world.
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Experience with immuno-pharmacological techniques including in vitro and ex-vivo immune cell-based assays, ELISA, MSD, flow cytometry based immune cell profiling. Knowledge of biomarker discovery and analysis is highly desirable while experience with in vivo pharmacology is preferable.
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Carry out sophisticated multi-color flow cytometry to characterize immune and cancer cells. This role presents an exciting chance to leverage your scientific knowledge in pioneering experiments designed to pinpoint and authenticate novel immunological/oncology targets through both in vitro and in vivo humanized models.
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The ideal candidate should possess strong laboratory experience and technical expertise in in vitro cellular immunology (including ELISA, MSD, Co-IP, assay development, tissue culture, flow cytometry, primary immune cell assays, cell fractionation) and ex vivo tissue processing and analysis.
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Familiarity with technologies commonly used to assess immunological endpoints, including ELISA/MSD, western blot/JESS and multi-parameter flow cytometry. The successful candidate will be responsible for generating preclinical data to support development of various compounds, via the execution of preclinical in vitro and supporting in vivo studies, to screen, profile and strengthen our mechanistic biological understanding of drug molecules.
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We are seeking a highly skilled PhD level Principal Scientist with proven experience in immunology and preclinical research to join our team. Oversee in vivo and in vitro studies, including development and optimization of disease models, study design, data collection, and interpretation.
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Flow cytometry, in vitro and supporting in vivo studies, min 3-5 years. Work within the project team to design, execute, troubleshoot, analyze and document in vitro and in vivo experiments to drive research data package generation to support IND-filing.
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We are seeking an in vivo Pharmacology Principal Scientist/Associate Director to join our Preclinical Efficacy and Safety group to contribute to advancing Adaptimmune’s early preclinical pipeline toward clinical evaluation.
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vivo cytometry scientist jobs in Waltham, MA
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