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We are seeking an experienced translational modeler eager to accelerate drug discovery & development by facilitating rigorous decision making with modeling & simulation, from target identification to first-in-human studies and beyond.
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Experience in in vivo pharmacology preferred. Drug discovery knowledge, biopharma CRO and relevant business experience required. GemPharmatech is a global company providing high-quality products and model systems for preclinical discovery, testing, and development of new drugs and therapeutic solutions.
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Planning and tracking activities in lead optimization, pharmacology, toxicology, and ADME studies, preclinical work for patient selection and indication expansion, drug supply, formulation development, clinical planning, and operations.
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Novartis has a wide portfolio with hundreds of drug discovery and clinical development projects and you will have opportunities to grow and develop as you apply modeling insights to diverse projects.
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Novartis has a broad portfolio of drug discovery and clinical development projects and you will have opportunities to grow and develop as you apply modeling insights to diverse projects.
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Requires a PhD in immunology, molecular biology, or cell biology plus postdoctoral experience (or equivalent relevant experience) with 10+ years' industry experience in research or drug development.
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We have developed a drug-discovery platform that integrates computational chemistry, structural biology, chemical biology, target-informed screening, and mechanism-driven pharmacology to develop small-molecule therapeutics that specifically modulate ferroptosis.
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Demonstrate a strong track record in early clinical drug development, including the principles of clinical pharmacology, biomarkers of target engagement, experimental medicine platforms, early clinical trial designs and conduct, and operational understanding for implementation.
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Applies quantitative skills, via modeling and simulation, to provide dose selection and complex issues at various stages of drug development. Interfaces with Research and works closely with discovery research during the pre-IND stages of drug development to ensure sufficient PK/PD knowledge exists for translation to the clinic.
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Design and execute preclinical studies to understand the pharmacokinetics (PK) and absorption, metabolism, distribution, and excretion (ADME) of drug candidates that support drug discovery, preclinical and clinical development.
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We are looking for an Associate Director in Clinical Pharmacology who will be a key member of our multidisciplinary drug development teams. You should be familiar with current scientific best practice and regulatory guidance in clinical pharmacology, pharmacometrics, pharmacokinetics and drug metabolism.
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A MS or PhD in Toxicology, Pharmacology, or other relevant field with minimum 12-15+ years of drug discovery and development experience in toxicology. In this role, you will lead the development and execution of the toxicology profiling of the companies drug candidates, including risk assessment /mitigation, and development of innovative toxicology strategies.
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About the company:Our client offers preclinical services for drug discovery, focused on the use of nonhuman primates to determine pharmacokinetics, pharmacology and toxicology of small molecules and biologics.
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Lead and oversee the development of clinical pharmacology strategies at different stages of drug development. Strong knowledge of pharmacokinetics and pharmacodynamics, with experience in drug development processes and regulatory interactions.
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The Vice President will drive the strategies and clinical plans across all phases of drug development. This position will work cross-functionally to ensure projects are coordinated with partners from multiple departments within Alkermes including regulatory, preclinical pharmacology and toxicology, CMC, new product planning, project management, patient engagement, health economics, legal, finance, medical affairs and commercial.
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pharmacology drug development jobs in Waltham, MA
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