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Experience with cell and gene therapy test methodologies (i.e. PCR, Flow Cytometry, ELISA, cell culture, cell-based assays). The ElevateBio ecosystem combines multiple R&D technology platforms – including Life Edit, a next-generation, full-spectrum gene editing platform; comprehensive cell engineering technologies; and an expanded viral and non-viral therapeutic delivery platform – with BaseCamp, its end-to-end genetic medicine cGMP manufacturing and process development business, to accelerate the discovery and development of advanced therapeutics.
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High level of technical expertise in some of these relevant areas: cell culture, protein/RNA/DNA analyses, in vivo animal studies (behavior, dosing, sample collection, stereotaxic surgery, etc.
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Expertise in primary human cell culture, multi-color flow cytometry, multiplex cytokine detection, functional immune cell assays (proliferation, cytotoxicity, chemotaxis) and assay development is essential.
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The successful candidate will work with his/her supervisor to design, plan and conduct molecular biology and cell culture experiments to evaluate strategies to improve AAV production platforms through expression vector modification and/or host cell line engineering.
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Experience with neural cell culture and/or stem cells highly desired. Preferred: 2-4 years laboratory experience in cell biology, microscopy, neurobiology, biochemistry, molecular biology or related field.
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Extensive hands-on experience with standard immunological techniques including multi-parameter flow cytometry, cell sorting, immunoassays such as ELISA, Cytotoxicity, in vitro co-culture assays (MLR, PBMC cultures, etc), and reporter bioassay development.
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Transient cell culture techniques such as transfection, cell number and viability monitoring, cell lysis and protein harvest Purification of proteins using liquid chromatography techniques.
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Helps to produce and isolates samples for proteomics studies using cell culture techniques, immunoprecipitation, subcellular fractionation methods and protein sample preparation from tissues and/or biofluids.
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Overview The Cell Therapies department at Dana Farber Cancer Institute has a great opportunity open for a Cell Therapy Coordinator. Requiring an ability to learn and work within multiple sets of regulatory compliance requirements, and performing complex decision tree procedures in more advanced levels of the job family, Cell Therapy Coordinators provide vital technical support infrastructure to a dynamic clinical environment of care.
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An ideal candidate should have a strong background in immortalized (hepatocytes) and primary cell culture (HSC, T cells) and have experience screening in these cell types using various CRISPR delivery systems, including RNPs and LNPs.
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Resumes are only accepted from third-party recruiters, staffing firms, or related agencies if a signed agreement is in place AND if external recruiting assistance is authorized by the People + Culture team for a specific position.
$202,250 a yearFull-timeExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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Department/Area Stem Cell and Regenerative Biology Position Description The Arlotta lab at HSCRB is working to identify the cellular and molecular pathways disrupted in brain disorders such as schizophrenia and autism, by utilizing recent advances in genetics and genomics.
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B.S./M.S. in Immunology, Cell Biology, Molecular Biology or a related scientific field. You have relevant experience in immunology, cell biology, molecular biology or a closely related field.
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Position is ideal for those experienced and/or have a strong interest in stem cell biology, disease modeling, neurobiology and developmental genetics. Must have experience in aseptic techniques including, but not limited to the culture of human cell lines, primary tissue culture and long-term cultures.
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Previous experience in managing technical interactions with CMOs, manufacturing of cell therapies, or product life cycle management is required. This is a senior level strategic role reporting to the VP of Cell Therapy Sciences at Takeda.
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full time or cell culture jobs in Waltham, MA
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