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The scientist will work flexibly across a variety of projects and have expertise or proficiency in Pharmacokinetics (PK)/pharmacodynamics (PD) including PK study design, data analysis, data review and bioanalysis in support of the Company’s pipeline, IND/CTA and NDA submissions.
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PhD in pharmacokinetics, clinical pharmacology, pharmacometrics, drug metabolism, pharmacology or related discipline. Demonstrated experience in clinical pharmacology and pharmacokinetics and advancing studies through clinical development.
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You will be the drug metabolism and pharmacokinetics (DMPK) lead on project teams discovering and developing small molecule modulators of clinically meaningful targets. Work closely with DMPK CROs to design, coordinate, monitor and manage external ADME and PK studies.
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Strong background in quantitative and qualitative research methodologies related to systems biology, pharmacokinetics, and PK/PD. The qualified candidate will apply knowledge and technical expertise to characterize systems biology, pharmacokinetics, and pharmacodynamics-related aspects facilitating research efforts across a diverse portfolio of diseases and therapeutic approaches.
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Lead the design of medicinal chemistry efforts by applying in-depth knowledge of structure-activity relationships (SAR), a profound understanding of target biology, and predictive methods for assessing on- and off-target activity, physical properties, pharmacokinetics/pharmacodynamics (PK/PD), and synthetic feasibility.
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Clinical Pharmacology and Pharmacometrics (CPP) provides characterization and prediction of the pharmacokinetics, pharmacodynamics and drug metabolism (PPDM) of the drug candidate in selected preclinical and all clinical areas, supporting drug discovery and medical therapeutics across many disease areas.
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Provide oversight to the development of Model Informed Drug Development (MIDD) plans, involving planning and execution of quantitative analyses which may include population pharmacokinetics, pharmacokinetics (PK)/pharmacodynamics (PD), exposure response, disease progression modeling, model-based meta-analysis, and decision analysis.
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D. or equivalent training in pharmacokinetics, pharmaceutical sciences, or related disciplines with 5 years of clinical pharmacology industry experience or M.S. with 10 years of relevant experience.
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Review preclinical study reports, in conjunction with Pharmacokinetics/DMPK and prepare regulatory submission documentation. Solid understanding of drug metabolism, bioanalysis, pharmacokinetics, preclinical pharmacology, PK/PD modeling and clinical study designs.
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This position will work in close collaboration with different functions, including preclinical toxicology, preclinical pharmacokinetics, translational medicine, clinical, operations, and regulatory affairs.
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We are seeking an exceptional leader in our Drug Metabolism and Pharmacokinetics (DMPK) function at Cerevel. PhD in Drug Metabolism, Pharmacokinetics, Chemistry or related scientific discipline with a minimum of 10 years of biotech/pharmaceutical drug discovery and development experience.
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Advanced degree in medicinal chemistry, computational chemistry, computational biology, computational chemical biology, or a related field. We are a driving force behind drug discovery, and we are now eagerly searching for an exceptional computational scientist like you to join our ranks.
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Moderna’s Bioanalytics group is seeking an Associate Director with strong hands-on experience in ligand-binding assays, including pharmacokinetics (PK), pharmacodynamics (PD), and anti-drug antibody (ADA) assessments, to quantify mRNAs, proteins, and antibodies against therapeutic proteins.
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Solid understanding of drug development, clinical research, study design, pharmacokinetics, and medical terminology. In addition to its wholly owned clinical assets, Dragonfly has a deep pipeline of wholly owned preclinical candidates discovered using its proprietary platform, as well as productive collaborations with Merck, AbbVie, Gilead and Bristol Myers Squibb in a broad range of disease areas.
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Our client offers preclinical services for drug discovery, focused on the use of nonhuman primates to determine pharmacokinetics, pharmacology and toxicology of small molecules and biologics. Our client offers preclinical services for drug discovery, focused on the use of nonhuman primates to determine pharmacokinetics, pharmacology and toxicology of small molecules and biologics.
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pharmacokinetics job in Somerville, MA
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