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Job Summary: As a Field Application Scientist specializing in Advanced Microscopy Applications for Cell and Tissue Biology, you will be at the forefront of translating cutting-edge microscopy technologies into impactful solutions for researchers in life sciences.
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Execute assays to assess gene and protein expression (e.g., qPCR, ELISA, Flow Cytometry, Fluorescence Microscopy), and biological effects (e.g., function, viability, enzymatic activity) in cell lines and primary and iPSC derived 3D organoid cultures.
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Experience with metallography, scanning electron microscopy, light microscopy, mechanical testing, or other materials characterization would be very helpful, but we will train highly motivated and qualified students.
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Analyze engineered tissue constructs utilizing electron microscopy, fluorescent microscopy, and assays for protein and gene expression among other techniques. Assemble and sterilize scaffolds, bioreactor components, and perfusion systems, partnering closely with the tissue engineering and cell biology teams.
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Sample preparation for fluorescence microscopy, fluorescence in situ hybridization (FISH) or immunohistochemistry. Designed protocols for preparation of samples in fluorescence in situ hybridization (FISH), immunohistochemistry or fluorescence microscopy.
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Expertise in molecular and cellular biology techniques, such as ddPCR, virus production and transductions, confocal microscopy, immunohistochemistry, flow cytometry. Expertise in molecular and cellular biology techniques, such as ddPCR, virus production and transductions, confocal microscopy, immunohistochemistry, flow cytometry.
$96,480 - $126,630 a yearFull-timeExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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There will also be opportunities to learn microscopy and mass spectrometry. Techniques used will include recombinant DNA cloning and analysis, protein purification and analysis, and yeast molecular genetics.
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Our customers are the leading OEM’s and researchers in high tech fields such as semiconductor, photonics, biomedical, aerospace, astronomy, metrology, scientific instrumentation, and scientific research in microscopy and beam lines.
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Experience in chemical and materials characterization techniques (spectroscopy, crystallography, microscopy) Flagship has created over 100 groundbreaking companies since 2000, including Moderna (NASDAQ: MRNA), Generate Biomedicines, Tessera Therapeutics, Indigo Ag, Inari Agriculture, and Sana Biotechnology.
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Experience with ELISA/ WB, IHC/ Immunofluorescence, and microscopy is a plus. Experience in therapeutic drug discovery, gene therapy, or RNA therapeutics. Experience with ELISA/ WB, IHC/ Immunofluorescence, and microscopy is a plus.
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Applicant should have knowledge of polymer chemistry and chemical/analytical methods such as Fourier transform infrared spectroscopy, mass spectrometry, scanning electron microscopy, and similar methods.
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Hands-on experience with cell-based assays and general molecular biology methods including, but not limited to, cell transfection, IVT, RNA extraction, qPCR, ddPCR, FACS, TapeStation, or Fragment Analyzer.
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Work will be performed under the supervision of Dr. Linda T. Nieman and Dr. David Ting (MGH Biomarker Discovery Lab, MGH Cancer Center)QualificationsThe MGH Krantz Family Center for Cancer Center Cartography Core is a new translational research facility that combines the latest advances protein and RNA biomarker staining with quantitative digital microscopy analytics to understand cancer biology.
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Proficiency in basic molecular biology including cloning, cell culture, immunostaining, and microscopy. PhD and/or MD in genetics/genomics, molecular biology, neuroscience, proteomics/biochemistry, or other related fields.
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In this position, you will be responsible for mammalian cell culture, in vitro cell based assays like Luciferase assay, cell titer Glo assay, ELISA, western blotting, qPCR, and microscopy. Perform a variety of in vitro and ex vivo assays, including but not limited to ELISA, qPCR, western blotting, enzymatic assay, immunohistochemistry, and immunofluorescence staining.
ExpandApply NowActive JobUpdated 6 days ago
microscopy job in Medford, MA
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