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Direct the planning and implementation of process development, scale-up, technology transfer, and validation efforts in drug substance manufacturing, ensuring strategic alignment and operational excellence.
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As part of the Discovery Biotherapeutics efforts at BMS, the Principal Scientist will play a key role in advancing antibody drug conjugates technologies at BMS. The Discovery Biotherapeutics team at BMS seeks to understand the structure and function of complex molecules such as bispecific antibodies, antibody drug conjugates and endogenous proteins in order to optimize their utility as therapeutic agents.
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Technical Expertise: Deep expertise in data science, computational biology, and AI/ML applications in early-stage biology, drug discovery, and translational research. Data Strategy Development: Define and implement a comprehensive data science strategy aligned with the company's R&D objectives, ensuring data science and AI/ML methodologies accelerate target discovery, drug development, and biomarker identification.
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Qualified candidates must have a PhD in synthetic/organic chemistry or related scientific field with 15+ years’ experience in drug substance development and manufacturing and a proven track record in developing and scaling up chemical process to kilo lab, pilot plant and commercial plant scales.
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You have a degree in a biological science and are capable of quickly coming up to speed on the biologics drug discovery process. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma.
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The ideal candidate should have an outstanding scientific reputation in the field of machine learning research for computational biology and a demonstrated passion for solving biological problems relevant to drug discovery.
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Interface with and drive collaboration between the various teams at Cellarity: Medicinal Chemistry, Biology, CMC, Drug Product, Clinical Development (DMPK, Preclinical Drug Safety, Clinical Pharmacology, Medicine, Regulatory, ClinOps) and with the Cellarity Leadership Team.
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The Chemical Biology and Proteomics (CBP) group at Biogen is seeking a creative and self-motivated Research Fellow to design, develop, and apply existing and new target identification strategies to various drug discovery programs.
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About the role: We are seeking a PhD and/or MD professional who is a scientific leader in the field of biologics drug discovery especially antibody drug conjugates (ADC). In-depth knowledge / background in Oncology and biotherapeutics (especially antibody drug conjugates) drug development; Strong publication track record and recognized as an expert within the field of oncology or biotherapeutics drug discovery.
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This position offers a unique opportunity to work in a dynamic and innovative environment developing your career at the interface of mechanistic research, drug discovery, and preclinical drug development.
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Perform quantitative bioanalytical immunoassay experiments to support non-regulated pharmacokinetic (PK) analyses of biotherapeutic drug candidates and evaluate anti-drug antibody (ADA) responses.
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PhD in cell or molecular biology or a related field, ideally with 2 or more years post-degree experience preferably in drug discovery and in an industry setting. In vivo drug candidate testing (e.g., mouse dosing; sample analysis.
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Company is currently seeking an Analytical Chemist in our Pivotal Attribute Sciences Department in Cambridge, MA. This team plays a crucial role in pivotal phase analytical support, including product development support, testing of drug substances and drug products.
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Development, optimization, qualification, transfer, validation, and routine execution of analytical methods for proteins, mAbs, drug conjugates using techniques pertinent to LC (SEC, RP, IEX), LCMS, ELISA, CE-SDS, icIEF, and other wet chemistry techniques.
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This position reports directly to the GVP Global Medical Affairs and will be evaluating, refining, updating, and growing the Drug Safety & Pharmacovigilance function at Kiniksa. A minimum of 15+ years’ experience as the Head of Drug Safety/Patient Safety/ Product Safety & Pharmacovigilance for a bio-pharmaceutical/pharmaceutical company.
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nih drug jobs Title: post doctoral fellow Company: Emory University in Lexington, MA
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