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Design, implement and optimize new technologies and assays to advance in vitro, ex vivo and translational efforts Design and execute ex vivo immuno-oncology assays, including flow cytometry-based and functional assays, to identify exploratory biomarkers, characterize immune cell populations and assess responses to treatment.
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Possess deep knowledge and expertise in immunology, biology, and multi-omics applications in translational research across various disease areas such as oncology (ONC), immuno-oncology (IO), immunity-driven diseases, and related treatment strategies.
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Contribute to pre-clinical projects by designing and developing well-defined mechanistic experiments and projects within Oncology and immuno-oncology research. Proven records by leveraging molecular/genetic tools for oncology research and mechanistic investigation.
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AVEO continues to develop FOTIVDA in immuno-oncology combinations in RCC and other indications, and has several other investigational programs in clinical development. The Director of Quality Assurance at AVEO Oncology reports to the Vice President Quality Assurance and is responsible for Quality Operations at AVEO including quality strategic leadership and compliance activities related to the cGMP manufacture and release of AVEO products.
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Demonstrated expertise in the application of methods of statistical learning and data mining to the integrative analysis of high-dimensional molecular profiling datasets in the immuno-oncology context.
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Minimum of 5 years of strategy and operations experience within the diagnostics (preferred) or biopharma ecosystem; experience with oncology clinical genomics, epigenomics, and/or liquid biopsy applications strongly preferred.
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Experience in immuno-oncology clinical development preferred with experience in protein. The successful Development Project Leader candidate has a deep understanding of the drug development process, with special emphasis on protein therapeutics and immune-oncology drug development.
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Previous lab experience is encouraged as the candidate will be expected to independently carry out essential research functions in the laboratory that will include, but are not limited to: Cell cultureWestern blot analysis (immuno-precipitations and immunoblotting)RNA/DNA extractions, PCR and RT-qPCRTransient transfection and lentiviral transductionPerforming cytotoxicity and proliferation assaysFlow cytometry assays and experience with analysis (DIVA, FLOW-JO) is preferred.
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Home Department: North 8 - Hematology/Oncology. North 8 is a 26-bed unit treating Bone Marrow Transplant and Hematology and Oncology patients. Comprised of Tufts Medical Center, Lowell General Hospital, MelroseWakefield Hospital, Lawrence Memorial Hospital of Medford, Care at Home - an expansive home care network, and large integrated physician network.
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Principal Scientist/Sr. Principal Scientist PK Sciences - Oncology. This role reports to a PK Sciences (PKS) Oncology group lead/unit head within Translational Medicine (TM) in Biomedical Research.
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The Department of Radiation Oncology Main Campus is comprised of two hospital departments and one physician group: Brigham And Women’s Hospital (BWH), Dana-Farber Cancer Institute (DFCI), and the Brigham and Women’s Physicians Organization (BWPO.
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Serve as an experienced thought leader for Immuno-Oncology & Translational Oncology within Takeda, guiding the research strategy and ensuring its successful execution while supporting talent development as a strong mentor and role model for cell engager research.
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Under the leadership of the MGB SVP for Operations (SVP) and the MGB President of the Cancer Institute (President), the Chief Administrator of the MGB Cancer Institute (CA) serves as the senior administrative executive for all cancer services across the health system, and has administrative oversight of all medical oncology, radiation oncology, and cancer surgery throughout MGB.
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ED; PACU/ASU; ICUs; Telemetry Units; SDU; IR, Interventional Cardiology (CCL/EP/Echo); L&D; Endoscopy, and APN Adult Oncology) Issuing Authority: American Heart Association Name: BCLS Issuing Authority: American Heart Association Name: PALS (Required Depts.
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Since its inception over a decade ago, CRISPR Therapeutics has transformed from a research-stage company advancing programs in the field of gene editing, to a company with a diverse portfolio of product candidates across a broad range of disease areas including hemoglobinopathies, oncology, regenerative medicine, cardiovascular and rare diseases.
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immuno oncology biopharma jobs in Chelsea, MA
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