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Ph. D. degree in molecular and cell biology, biochemistry, biology, biotechnology, or related pharmaceutical science; Responsible for cell line development (CLD) activities including transfection, stable selection, cell culture maintenance, clone selection, and genetic engineering and characterization of mammalian cell lines for clinical and commercial production.
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Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFomeTM was developed in Professor George Church’s lab, a pioneer in synthetic biology, and allows for the development of unique cell therapies with significantly streamlined manufacturing, improved cell quality, efficiency and speed.
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The general curiosity about the current state-of-the-art neuroscience, tumor biology, cell culture, imaging, electrophysiology, and animal work is expected. Our multidisciplinary group combines experience in cell therapy, transplantation, stem cell differentiation, retinal development, retinal cell biology, retinal electrophysiology, small and large animal models of disease, bioinformatics, and single-cell and spatial advanced transcriptomics analysis.
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Proven track record of leading successful in vitro pharmacology efforts in the field of Cell Therapy, including assay development and validation, candidate screening, and mechanism of action studies.
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Lead with hands-on support in commercial cell line development contract campaigns and single-cell assay development. Scientist/Senior Scientist, Cell Line Development. At OneCyte, you'll play a pivotal role in advancing biotechnology through commercial cell line development contract campaigns, cutting-edge R&D efforts, and the development of state-of-the-art technologies.
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Independently develop and execute quantitative assays (ELISA, cell signaling, flow cytometry) and establish primary cell-based assays with a variety of immune cell subtypes (including lymphoid and myeloid cells.
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Domain expertise in cell or human physiology, single-cell genomics, computational biology, or bioengineering is a plus. Our current work merges the Klarman Cell Observatory’s historical strengths in single cell sequencing and technology development with the Xavier lab’s expertise in organ biology, immunology, and human genetics.
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Cellular and molecular biology methodologies, e.g., mammalian cell culture; in vitro screening; cell-based assays; RNA extraction and RT-qPCR. Experience in cellular and molecular biology is essential (e.g., mammalian cell culture, cell-based assays, quantitative real-time PCR.
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To do this, we are gathering a team with highly diverse skills and experiences, ranging from genetic engineering, plant cell culture, sterile process development, bioreactor design, mathematics, statistics agriculture, high-performance automation, stylists, illustrators, fashion designers, creative business development, marketing and branding strategies.
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The Senior Director, CMC Product Leader for Biopharmaceutical Sciences-Cell & Gene Therapy, will lead the CMC functional team dedicated to a single cell therapy or biological product. Minimum of 10 years of experience in CMC development and manufacturing within the biotechnology or pharmaceutical industry, with a focus on cell therapy or regenerative medicine.
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Proficient in industry-standard cell-based assay and bioanalytical techniques including TR-FRET, ELISA, flow cytometry, and reporter gene; experience with cellular/high content imaging and image analysis highly desirable.
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We are seeking a Scientist / Senior Scientist specializing in cotton fiber development to guide our efforts in isolating, cultivating, and optimizing stable plant stem cell lines for fiber production.
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Experience with in vivo cell therapy and/or virus like particle (VLP) application is preferred. Experience with mammalian cell culture, PCR, and related cell/molecular biology methods.
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We utilize immunofluorescence microscopy, cell and molecular biology, DNA damage repair, flow cytometry, and various sequencing assays on cell lines and patient-derived organoids to study DNA replication and cell cycle dynamics in different disease or pre-cancerous settings.
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Principal Scientist / Distinguished Scientist, Cell Biology (Cotton Fiber Development) Ph. D. with a focus on cotton fiber development or cell wall biology and a minimum of 7+ years of hands-on experience in plant tissue culture.
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cell phone jobs Title: general Company: Papa in Cambridge, MA
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