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We are expanding our capabilities in informatics across multiple drug discovery platforms, including DNencoded library (DEL) screening, peptide-display discovery, support for RNbased therapeutics, parallel medicinal chemistry (PMC), targeted protein degradation, and high-throughput screening (HTS.
ExpandApply NowActive JobUpdated 7 days ago - UpvoteDownvoteShare Job
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He/she will also be supporting external collaborations as well as leading the screening activities for small molecule internal drug discovery projects leveraging a highly outsourced CRO model.
Full-timeExpandApply NowActive JobUpdated 6 days ago - UpvoteDownvoteShare Job
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RESPONSIBILITIES Reporting to the Director, Biotherapeutics the Senior Scientist will be part of the Biotherapeutics Drug Discovery team. The successful applicant will support therapeutic antibody discovery and optimization campaigns – including leading reagent generation strategies, developing antibody campaign workplans and screening funnels, overseeing the execution of the campaigns through CRO partners, and optimizing lead antibodies for development candidate selection.
Full-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Expertise with traditional computational chemistry, which includes docking, pharmacophore modeling, homology modeling, and structure- and ligand-based virtual screening. Leveraging their cutting edge chemical biology platform and combining this with computational tools and machine learning, they are accelerating molecular glue discovery across oncology and immunology indications.
ExpandApply NowActive JobUpdated 13 days ago - UpvoteDownvoteShare Job
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Able to interact effectively with multiple scientific stakeholders (including data science, screening, DMPK, safety, translational, clinical) to drive drug discovery programs. Our labs include state-of-the-art capabilities that support the variety of disciplines located at the site, including medicinal and process chemistry, in-vitro and in-vivo biology, microscopy, DMPK, drug safety, chemical and structural biology, automation and screening, and more.
Full-timeExpandApply NowActive JobUpdated 11 days ago - UpvoteDownvoteShare Job
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Act as the Cell Pharmacology representative or Profiling Lead in efforts to advance drug discovery projects in a multidisciplinary, collaborative project team setting; build and support cell-based assay screening strategies to achieve project goals, interpret and communicate results, and recommend next steps to the project teams.
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In this position, you will join the Department of Bioinformatics and AI in Simcere BIC, supporting early drug discovery and other R&D teams for novel cancer drug development for cancer and autoimmune diseases.
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Research experience in drug discovery context is highly desired. At Rgenta Therapeutics, we focus on unlocking the therapeutic potentials of targets that are highly disease relevant but previously undruggable through our proprietary RNA targeting platforms leveraging our deep knowledge in genomics, computational biology, screening, and chemistry.
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Collaborate with a world class, multidisciplinary team of drug discovery scientists from medicinal and platform chemistry, DEL, in vitro pharmacology, biology, and data science to advance multiple small molecule programs as new clinical candidates for the treatment of several diseases.
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This candidate will spearhead scientific and technical advancements in cell-based assay development and high throughput DNA library screening, building our drug discovery initiatives.
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This individual would own the implementation and execution of in vitro assay development and screening strategies, assist in lab automation, manage the lab operations and activities of junior level scientists and CROs, and contribute to progressing lead compounds through our drug discovery process.
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Our research focuses on the application of clinical genomics for development of targeted therapy approaches for acute leukemia, drug testing and combination screening with the ultimate goals of 1) improving understanding of leukemia biology and 2) translating bench discovery to clinical care.
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The DeKosky Laboratory for Immune Engineering and Drug Discovery ( , Google Scholar: ) is seeking to grow in the hiring of a new postdoctoral researcher to apply high-throughput antibody functional screening against a variety of human diseases, including infectious diseases and other targets in cancer and autoimmunity.
Full-timeExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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Our drug discovery engine is differentiated by massively parallel screening in vivo from the beginning of our discovery process. We combine this and other high-throughput protein engineering approaches with computational design to create antibody-like drugs and other biologics.
Full-timeExpandApply NowActive JobUpdated 3 months ago - UpvoteDownvoteShare Job
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A PhD in life sciences or related field with at least five years of experience in RNA drug discovery within or intersecting with the pharmaceutical or biotech industry. You will be responsible for establishing the technologies required to identify, characterize and optimize compounds in drug discovery programs along with the infrastructure, and internal expertise necessary to realize GSK’s future RNA therapeutic ambitions.
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drug screening discovery jobs in Cambridge, MA
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