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Analytical Skill, Analytical Skill, Analytical Thinking, Chemical Biology, Chemistry, Clinical Trials, Collaboration, Communication Skills, Curiosity, Data, Data Analysis, Design Of Experiments, Detail-Oriented, Drug Development, Drug Discovery, Ethics, Gene Therapy, Immunology, Inventory Management, Laboratory, Lifesciences, Machine Learning (Ml), Management, Medical Research, Molecular Biology {+ 10 more.
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Oversee in vivo and in vitro studies, including development and optimization of disease models, study design, data collection, and interpretation. Develop and validate immunological assays (, flow cytometry, ELISA, CyTOF, cytokine profiling) to evaluate drug candidates' efficacy and mechanism of action.
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The Senior Scientist / Principal Scientist will follow programs as they proceed through development, supporting the overall drug substance development and manufacturing activities.
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Proven track record of scientific leadership and accomplishments in biotechnology, with significant experience in drug discovery and development. Reporting to the CEO, the Chief Scientific Officer (CSO) will play a pivotal role in leading our scientific research and development efforts to drive scientific strategy and to shape the pipeline of novel CNS therapies.
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Development and application of human cardio-metabolic disease cell models to support TDE strategy in obesity target discovery and validation, and accelerate advancement of new drug targets into the NN pipeline.
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Design, execute and manage in vitro biology functional experiments that support preclinical drug discovery including candidate screening, lead selection, and target validation. The role will be responsible for leading in vitro assay development for molecule screening, lead characterization and development candidate selection.
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We are a market leader in automated bio sample management solutions and genomic services across areas such as drug development, clinical and advanced cell therapies for the industry's top pharmaceutical, biotech, academic and healthcare institutions globally.
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Responsibilities Support the development of the Drug Substance strategy and oversee manufacturing of preclinical and clinical material. Senior Director, Drug Substance Position Summary Reporting to the VP, Head of CMC Development, the Senior Director, Drug Substance will be responsible for leading the drug substance team in development and manufacturing as part of PepGen ́s CMC team.
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In addition, the Director will work closely with R&D, Health Economics and Market Access (HEMA), and Business Development, Global Commercial Strategy Organization (GCSO), Pricing, Med Affairs, and Real World Evidence (RWE) to construct the new product portfolio and commercialization strategies.
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We advance the science of our pharmaceutical and biopharmaceutical customers through the drug development process, from early-phase R&D through clinical trials and GMP commercial product support.
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The Alloy Global Bioanalytics group provides bioanalytical support to all Alloy activities, including assay development, quality control and high-throughput characterization of antibodies, TCR mimics and other modalities.
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Qualified candidates must have a PhD in synthetic/organic chemistry or related scientific field with 15+ years’ experience in drug substance development and manufacturing and a proven track record in developing and scaling up chemical process to kilo lab, pilot plant and commercial plant scales.
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Support the planning and implementation of manufacturing process development, scale-up, technology transfer, and validation efforts in API, drug product, and primary packaging, ensuring strategic alignment and operational excellence.
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Senior Scientist, Mass Spectrometry, Early Oncology Join our Boston R&D chemistry team as a Senior Scientist, where you'll use your expertise in small-molecule mass spectrometry to analyze a wide range of drug-like small molecules, linkers, payloads, and new modalities using UHPLC-MS techniques.
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Provide and present results in consultation with supervisor to support drug substance and drug product development. Process Development Senior Associate, Analytical Chemist.
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drug development jobs in Cambridge, MA
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