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You’ll identify emerging practices for biologics cell line development and manufacturing to shape scientific strategies and continued innovation. We are seeking aSenior Scientist, Biologics Cell Line Development to join our team in Boston, MA and help push the boundaries of biotherapeutic cell line development.
Full-timeExpandApply NowActive JobUpdated 11 days ago - UpvoteDownvoteShare Job
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Execute experiments to support Cell Line Development and Scale up of PSC-derived cells. Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFome was developed in Professor George Churchs lab, a pioneer insynthetic biology, and allows for the development of unique cell therapies with significantly streamlined manufacturing, improved cell quality, efficiency, and speed.
Full-timeExpandApply NowActive JobUpdated 28 days ago - UpvoteDownvoteShare Job
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The successful candidate should have strong experience in molecular and cell biology techniques including culture of primary cells and cell lines, transient/stable transfection and cell line selection, flow cytometry, ELISA and western blot.
ExpandApply NowActive JobUpdated 14 days ago - UpvoteDownvoteShare Job
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Job Title: Postdoctoral Fellow Location: Cambridge, MA Duration: 12 months on Contract Description: Highlights: Strong Molecular Biology Description The Biological Process Development recently has Cell Line Development (CLD) group is responsible for producing cell lines that express clinical grade therapeutic proteins and viral vectors for Cell and Gene Therapies.
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Position Summary:ultrafocused – Work together to fearlessly uncover new possibilitiesReporting to the Senior Research Associate, the Co-Op will support the team by maintaining stock cell cultures and performing standard molecular biology assays.
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Principal Associate Scientist / Senior Principal Associate Scientist, Hit Identification And Biology
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Execute cell line engineering workflows (CRISPR, viral transduction, transfection) to support antibody discovery and screening/characterization. Dragonfly Therapeutics seeks an experienced and motivated Principal/Senior Principal Associate Scientist with a strong background in cell biology/immunology to support the discovery and development of cancer and autoimmune therapies.
ExpandApply NowActive JobUpdated 11 days ago - UpvoteDownvoteShare Job
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The Senior Director of Cell Line Development (CLD) will lead and direct the production of novel viral vector plasmids and high-producing, high quality packaging and/or producer cell lines for AAV. They will also be responsible for new technology evaluations, due diligence activities, and cell line strategy across the entire product lifecycle.
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Develop approaches using biophysical, biochemical, immunoassays, cell-based assays, and molecular assays with line-of-sign to GMPProvide technical guidance and hands on support for method development and testingCollaborate closely with cross-functional teams to support research, formulation, and process development efforts.
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Understanding of cell line development and CMC activities. Experience developing & implementing high-throughput screening assays including, ELISA, cell-based binding FACS, reporter cell lines, HTRF, AlphaLISA.
Full-timeExpandApply NowActive JobUpdated 14 days ago - UpvoteDownvoteShare Job
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ReciBioPharm, the biologics business unit of ReciPharm AB, is seeking a talented individual with background in Strain Engineering & Development to join our Plasmid Upstream Process Development team in Nucleic Acid PD Group in Watertwon, MA. The Sr. Scientist/Scientist will be accountable for developing bacterial cell line for plasmid DNA production and quality control of plasmid DNA product.
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Public Transportation is available to the College via the MBTA Orange Line Roxbury Crossing Station & connecting bus stops which is an eight-minute walk to the campus. The Director of the Business Innovation Center (BIC) leads the planning for and implementation of programs, partnerships, and strategic initiatives; oversees the Center's program managers and administrative staff; leads fundraising and resource development effort.
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At least 2 years of experience in one or more of the following areas biopharma R&D, antibody discovery, protein engineering, protein expression and purification, cell line development, bioprocess development, CMC, or biopharma production with bioanalytic, or lab automation.
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Prior experience must include: Development of stirred-tank, wave, and static bioreactor processes for cell and gene therapy applications scalable to at least 25 L (3 yrs); adaptation of mammalian cells to culturing in BioFlo, XDR, Xuri, and G-Rex platforms (3 yrs); planning DOE-based studies and performing multivariate statistical analysis on large data sets in JMP and Minitab (2 yrs); Programming liquid handling robots and high-throughput systems (2 yrs.
Full-timeExpandApply NowActive JobUpdated 23 days ago - UpvoteDownvoteShare Job
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From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. Position Summary CDLs are matrix leaders and managers who lead, develop, motivate and achieve results through teams; demonstrate a commitment to the development of a resilient attitude, embrace change and have an unwavering commitment to our People StrategyServes as the clinical point of accountability for the Development Team and is responsible for navigating the overall clinical development plan for complex programs that have a large impact on the business.
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The ideal candidate would have extensive experience in cell line and upstream process development. Ph. D. in biochemical engineering, chemical engineering, biochemistry, or appropriate technical discipline with 12-15 years industrial bioprocess development/scale-up and manufacturing experience.
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cell line development jobs in Cambridge, MA
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